Potassium two pore domain channel subfamily K member 4
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: G3V8V5
additional property: PropertyValue
  property ID: P361
  value: Two pore domain potassium channel, TRAAK
additional property: PropertyValue
  property ID: P361
  value: Potassium channel domain, protein family
additional property: PropertyValue
  property ID: P527
  value: Potassium channel domain
additional property: PropertyValue
  property ID: P637
  value: NP_446256
additional property: PropertyValue
  property ID: P637
  value: XP_006230696
additional property: PropertyValue
  property ID: P637
  value: XP_008758276
additional property: PropertyValue
  property ID: P680
  value: potassium channel activity
additional property: PropertyValue
  property ID: P680
  value: potassium ion leak channel activity
additional property: PropertyValue
  property ID: P680
  value: temperature-gated cation channel activity
additional property: PropertyValue
  property ID: P681
  value: plasma membrane
additional property: PropertyValue
  property ID: P681
  value: integral component of plasma membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: ion transport
additional property: PropertyValue
  property ID: P682
  value: potassium ion transport
additional property: PropertyValue
  property ID: P682
  value: memory
additional property: PropertyValue
  property ID: P702
  value: Kcnk4
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000028704
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 9
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 9
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: G3V8V5
    source count: 1
    confidence: 0.2
  P361:
    value: Q24782438
    source count: 1
    confidence: 0.2
    value label: Two pore domain potassium channel, TRAAK
  P361:
    value: Q83133767
    source count: 1
    confidence: 0.2
    value label: Potassium channel domain, protein family
  P527:
    value: Q24722427
    source count: 1
    confidence: 0.2
    value label: Potassium channel domain
  P637:
    value: NP_446256
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006230696
    source count: 1
    confidence: 0.2
  P637:
    value: XP_008758276
    source count: 1
    confidence: 0.2
  P637:
    value: XP_008758277
    source count: 1
    confidence: 0.2
  P637:
    value: XP_008758278
    source count: 1
    confidence: 0.2
  P680:
    value: Q14865153
    source count: 5
    confidence: 1.0
    value label: potassium channel activity
  P680:
    value: Q21119812
    source count: 1
    confidence: 0.2
    value label: potassium ion leak channel activity
  P680:
    value: Q21095674
    source count: 1
    confidence: 0.2
    value label: temperature-gated cation channel activity
  P680:
    value: Q21119850
    source count: 2
    confidence: 0.4
    value label: mechanosensitived potassium channel activity
  P681:
    value: Q29548
    source count: 1
    confidence: 0.2
    value label: plasma membrane
  P681:
    value: Q14859540
    source count: 3
    confidence: 0.6
    value label: integral component of plasma membrane
  P681:
    value: Q14349455
    source count: 2
    confidence: 0.4
    value label: membrane
  P681:
    value: Q14327652
    source count: 1
    confidence: 0.2
    value label: integral component of membrane
  P681:
    value: Q21096388
    source count: 1
    confidence: 0.2
    value label: potassium channel complex
  P682:
    value: Q14859673
    source count: 1
    confidence: 0.2
    value label: ion transport
  P682:
    value: Q14860315
    source count: 1
    confidence: 0.2
    value label: potassium ion transport
  P682:
    value: Q492
    source count: 1
    confidence: 0.2
    value label: memory
  P682:
    value: Q2734305
    source count: 2
    confidence: 0.4
    value label: sensory perception of pain
  P682:
    value: Q21119811
    source count: 1
    confidence: 0.2
    value label: stabilization of membrane potential
  P702:
    value: Q24406170
    source count: 1
    confidence: 0.2
    value label: Kcnk4
  P703:
    value: Q184224
    source count: 1
    confidence: 0.2
    value label: brown rat

value: ENSRNOP00000028704
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
stated in qid: Q28580851
retrieved: 2019-02-14

source: Synergistic interaction and the role of C-terminus in the activation of TRAAK K+ channels by pressure, free fatty acids and alkali
stated in qid: Q28582799
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: mRNA expression alteration of two-pore potassium channels in the brain of beta-amyloid peptide25-35-induced memory impaired rats
stated in qid: Q28568558
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q28556089
domain: protein
level: standard
html url: https://4ort.xyz/entity/potassium-two-pore-domain-channel-subfamily-k-member-4-q28556089
markdown url: https://4ort.xyz/entity/potassium-two-pore-domain-channel-subfamily-k-member-4-q28556089.md
facts url summary: https://4ort.xyz/entity/potassium-two-pore-domain-channel-subfamily-k-member-4-q28556089/facts.json
facts url standard: https://4ort.xyz/entity/potassium-two-pore-domain-channel-subfamily-k-member-4-q28556089/facts.json
facts url full: https://4ort.xyz/entity/potassium-two-pore-domain-channel-subfamily-k-member-4-q28556089/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-12T05:20:15.368638Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:42:22.550026+00:00Z