Polymerase (DNA directed), beta
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P361
  value: DNA polymerase family X, beta-like
additional property: PropertyValue
  property ID: P361
  value: DNA polymerase lambda lyase domain superfamily
additional property: PropertyValue
  property ID: P361
  value: DNA polymerase, thumb domain superfamily
additional property: PropertyValue
  property ID: P527
  value: DNA-directed DNA polymerase X
additional property: PropertyValue
  property ID: P527
  value: DNA polymerase beta, palm domain
additional property: PropertyValue
  property ID: P527
  value: Helix-hairpin-helix DNA-binding motif, class 1
additional property: PropertyValue
  property ID: P637
  value: NP_035260
additional property: PropertyValue
  property ID: P637
  value: XP_006509093
additional property: PropertyValue
  property ID: P637
  value: XP_011240428
additional property: PropertyValue
  property ID: P680
  value: transferase activity
additional property: PropertyValue
  property ID: P680
  value: nucleotidyltransferase activity
additional property: PropertyValue
  property ID: P680
  value: microtubule binding
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: spindle microtubule
additional property: PropertyValue
  property ID: P681
  value: synaptonemal complex
additional property: PropertyValue
  property ID: P682
  value: neuron apoptotic process
additional property: PropertyValue
  property ID: P682
  value: somatic hypermutation of immunoglobulin genes
additional property: PropertyValue
  property ID: P682
  value: homeostasis of number of cells
additional property: PropertyValue
  property ID: P702
  value: Polb
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000033938
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000148216
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 19
      unique citations norm: 0.007
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 19
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q8K409
    source count: 1
    confidence: 0.2
  P361:
    value: Q24784783
    source count: 1
    confidence: 0.2
    value label: DNA polymerase family X, beta-like
  P361:
    value: Q41796746
    source count: 1
    confidence: 0.2
    value label: DNA polymerase lambda lyase domain superfamily
  P361:
    value: Q41798246
    source count: 1
    confidence: 0.2
    value label: DNA polymerase, thumb domain superfamily
  P361:
    value: Q83165811
    source count: 1
    confidence: 0.2
    value label: DNA polymerase beta, palm domain, protein family
  P361:
    value: Q83163618
    source count: 1
    confidence: 0.2
    value label: Helix-hairpin-helix DNA-binding motif, class 1, protein family
  P527:
    value: Q24724839
    source count: 1
    confidence: 0.2
    value label: DNA-directed DNA polymerase X
  P527:
    value: Q24786633
    source count: 1
    confidence: 0.2
    value label: DNA polymerase beta, palm domain
  P527:
    value: Q24783550
    source count: 1
    confidence: 0.2
    value label: Helix-hairpin-helix DNA-binding motif, class 1
  P527:
    value: Q24769246
    source count: 1
    confidence: 0.2
    value label: DNA polymerase lambda, fingers domain
  P527:
    value: Q24779789
    source count: 1
    confidence: 0.2
    value label: DNA polymerase family X, binding site
  P637:
    value: NP_035260
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006509093
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011240428
    source count: 1
    confidence: 0.2
  P637:
    value: XP_030099215
    source count: 1
    confidence: 0.2
  P637:
    value: XP_036009721
    source count: 1
    confidence: 0.2
  P680:
    value: Q14840131
    source count: 1
    confidence: 0.2
    value label: transferase activity
  P680:
    value: Q14865136
    source count: 2
    confidence: 0.4
    value label: nucleotidyltransferase activity
  P680:
    value: Q14762611
    source count: 2
    confidence: 0.4
    value label: microtubule binding
  P680:
    value: Q14859873
    source count: 4
    confidence: 0.8
    value label: lyase activity
  P680:
    value: Q14599289
    source count: 2
    confidence: 0.4
    value label: enzyme binding

value: Q79899
source count: 4
confidence: 0.8
value label: cytoplasm

value: Q14762602
source count: 2
confidence: 0.4
value label: spindle microtubule

value: Q2064069
source count: 1
confidence: 0.2
value label: synaptonemal complex

value: Q189933
source count: 2
confidence: 0.4
value label: microtubule

value: Q40260
source count: 4
confidence: 0.8
value label: nucleus

value: Q14818077
source count: 1
confidence: 0.2
value label: neuron apoptotic process

value: Q14911681
source count: 1
confidence: 0.2
value label: somatic hypermutation of immunoglobulin genes

value: Q14905398
source count: 1
confidence: 0.2
value label: homeostasis of number of cells

value: Q14819632
source count: 1
confidence: 0.2
value label: response to hyperoxia

value: Q332154
source count: 1
confidence: 0.2
value label: ageing

value: Q18253150
source count: 1
confidence: 0.2
value label: Polb

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000033938
source count: 1
confidence: 0.2

value: ENSMUSP00000148216
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: The murine DNA glycosylase NEIL2 (mNEIL2) and human DNA polymerase beta bind microtubules in situ and in vitro
stated in qid: Q24296253
retrieved: 2019-02-14

source: Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally
stated in qid: Q28592782
retrieved: 2018-01-01

source: Normal immune function in young and old DNA polymerase-beta deficient mice
stated in qid: Q28508635
retrieved: 2018-01-01

source: Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage
stated in qid: Q28505163
retrieved: 2018-01-01

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-01

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2018-09-10

source: Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally
stated in qid: Q28592782
retrieved: 2019-02-14

source: Normal immune function in young and old DNA polymerase-beta deficient mice
stated in qid: Q28508635
retrieved: 2019-02-14

source: Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage
stated in qid: Q28505163
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function
stated in qid: Q24306488
retrieved: 2019-02-14

source: p53 Deficiency rescues neuronal apoptosis but not differentiation in DNA polymerase beta-deficient mice
stated in qid: Q28585654
retrieved: 2019-02-14

source: Mutation of POLB Causes Lupus in Mice
stated in qid: Q28513579
retrieved: 2019-02-14

source: Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase beta-defective mouse cells
stated in qid: Q24294984
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21498319
domain: protein
level: standard
html url: https://4ort.xyz/entity/polymerase-dna-directed-beta
markdown url: https://4ort.xyz/entity/polymerase-dna-directed-beta.md
facts url summary: https://4ort.xyz/entity/polymerase-dna-directed-beta/facts.json
facts url standard: https://4ort.xyz/entity/polymerase-dna-directed-beta/facts.json
facts url full: https://4ort.xyz/entity/polymerase-dna-directed-beta/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T17:47:44.418480Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:57:14.966657+00:00Z