# Polycystin 2 like 1, transient receptor potential cation channel

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21126833](https://www.wikidata.org/wiki/Q21126833)  
**Source**: https://4ort.xyz/entity/polycystin-2-like-1-transient-receptor-potential-cation-channel


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9P0L9)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
6. [Crystal structure and characterization of coiled-coil domain of the transient receptor potential channel PKD2L1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
7. [The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
8. [Polycystin-L is a calcium-regulated cation channel permeable to calcium ions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
9. [Direct binding of alpha-actinin enhances TRPP3 channel activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P0L9&geneProductId=UniProtKB:Q9P0L9)
11. [Direct recording and molecular identification of the calcium channel of primary cilia.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P0L9&geneProductId=UniProtKB:Q9P0L9)
12. [Troponin I binds polycystin-L and inhibits its calcium-induced channel activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
13. [Direct recording and molecular identification of the calcium channel of primary cilia.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
14. [Interaction between PKD1L3 and PKD2L1 through their transmembrane domains is required for localization of PKD2L1 at taste pores in taste cells of circumvallate and foliate papillae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
15. [Polycystin-2 interacts with troponin I, an angiogenesis inhibitor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
16. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
17. [Cryo-EM structure of the polycystin 2-l1 ion channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
19. [Identification of PKD2L, a human PKD2-related gene: tissue-specific expression and mapping to chromosome 10q25](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
20. [Identification of PKDL, a Novel Polycystic Kidney Disease 2-Like Gene Whose Murine Homologue Is Deleted in Mice with Kidney and Retinal Defects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
21. [Sour ageusia in two individuals implicates ion channels of the ASIC and PKD families in human sour taste perception at the anterior tongue](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P0L9&geneProductId=UniProtKB:Q9P0L9)
22. [Sour ageusia in two individuals implicates ion channels of the ASIC and PKD families in human sour taste perception at the anterior tongue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P0L9)
23. [Crystal structure and characterization of coiled-coil domain of the transient receptor potential channel PKD2L1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P0L9&geneProductId=UniProtKB:Q9P0L9)
24. Ensembl Release 99
25. Transporter Classification database