# Polycystin 1, transient receptor potential channel interacting

> mammalian protein found in Homo sapiens

**Wikidata**: [Q2044253](https://www.wikidata.org/wiki/Q2044253)  
**Source**: https://4ort.xyz/entity/polycystin-1-transient-receptor-potential-channel-interacting-q2044253


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P98161)
3. Q20641742
4. [Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
5. [PKD1 interacts with PKD2 through a probable coiled-coil domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
7. [ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
8. [Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
9. [Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
10. [Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
11. [Specific association of the gene product of PKD2 with the TRPC1 channel](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
12. [A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
13. [Structural and molecular basis of the assembly of the TRPP2/PKD1 complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
14. [Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
15. [Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
16. [The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
17. [Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
18. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
19. [Identification and proteomic profiling of exosomes in human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
20. [Strong homophilic interactions of the Ig-like domains of polycystin-1, the protein product of an autosomal dominant polycystic kidney disease gene, PKD1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
21. [Expression of PKD1 and PKD2 transcripts and proteins in human embryo and during normal kidney development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
22. [Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
23. [Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
24. [Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P98161&geneProductId=UniProtKB:P98161)
25. Ensembl Release 99
26. Transporter Classification database