# Polycystin 1, transient receptor potential channel interacting

> mammalian protein found in Mus musculus

**Wikidata**: [Q14914569](https://www.wikidata.org/wiki/Q14914569)  
**Source**: https://4ort.xyz/entity/polycystin-1-transient-receptor-potential-channel-interacting-q14914569


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O08852)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
5. [PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2](http://www.ebi.ac.uk/QuickGO/annotations?protein=O08852&geneProductId=UniProtKB:O08852)
6. [Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O08852&geneProductId=UniProtKB:O08852)
7. [Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
8. [Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
9. [PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
10. [Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
11. [Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O08852&geneProductId=UniProtKB:O08852)
13. [Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
14. [Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
15. [Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
16. [Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
17. [Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
18. [Localization of transient receptor potential ion channels in primary and motile cilia of the female murine reproductive organs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
19. [Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism](http://www.ebi.ac.uk/QuickGO/annotations?protein=O08852&geneProductId=UniProtKB:O08852)
20. [Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
21. [Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
22. [A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O08852&geneProductId=UniProtKB:O08852)
23. [A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
24. [Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
25. [Pkd1 and Pkd2 are required for normal placental development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
26. [Loss of PKD1 and loss of Bcl-2 elicit polycystic kidney disease through distinct mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
27. [Global genetic analysis in mice unveils central role for cilia in congenital heart disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
28. [Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
29. [Pkd1 regulates lymphatic vascular morphogenesis during development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
30. [Polycystin 1 is required for the structural integrity of blood vessels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
31. [Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08852)
32. ensembl Release 106