# Poly (ADP-ribose) polymerase 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28559569](https://www.wikidata.org/wiki/Q28559569)  
**Source**: https://4ort.xyz/entity/poly-adp-ribose-polymerase-1-q28559569


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P27008)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
5. [Poly(ADP-ribose) Polymerase 1 Is Indispensable for Transforming Growth Factor-β Induced Smad3 Activation in Vascular Smooth Muscle Cell](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
6. [Effect of aging and oxidative/genotoxic stress on poly(ADP-ribose) polymerase-1 activity in rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
7. [Misregulation of poly(ADP-ribose) polymerase-1 activity and cell type-specific loss of poly(ADP-ribose) synthesis in the cerebellum of aged rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
9. [The orphan receptor NOR1 participates in isoprenaline-induced cardiac hypertrophy by regulating PARP-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
10. [Isolation of cDNA encoding full‐length rat (Rattus norvegicus) poly(ADP‐ribose) polymerase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
11. [SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
12. [Poly(ADP-ribose) polymerase 1 is a key regulator of estrogen receptor α-dependent gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
13. [PolyADP-ribosylation is involved in neurotrophic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
14. [Modulation of poly(ADP-ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
15. [Poly (ADP-ribose) polymerase and DNA-dependent protein kinase: differential activation in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
16. [Regulation of myofibroblast differentiation by poly(ADP-ribose) polymerase 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
17. [Beta-amyloid activates PARP causing astrocytic metabolic failure and neuronal death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
18. [Zinc Promotes the Death of Hypoxic Astrocytes by Upregulating Hypoxia‐Induced Hypoxia‐Inducible Factor‐1alpha Expression via Poly(ADP‐ribose) Polymerase‐1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
19. [Poly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27008)
20. ensembl Release 106