# Poly(A) binding protein cytoplasmic 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21112715](https://www.wikidata.org/wiki/Q21112715)  
**Source**: https://4ort.xyz/entity/poly-a-binding-protein-cytoplasmic-1-q21112715


## References

1. UniProt
2. [BioGRID](https://thebiogrid.org/news/227)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P11940)
4. Q20641742
5. [Poly(A)-binding protein and eRF3 are associated in vivo in human and Xenopus cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
6. [Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
7. [Phosphorylation of Human Tristetraprolin in Response to Its Interaction with the Cbl Interacting Protein CIN85](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
8. [La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
9. [Paip1 interacts with poly(A) binding protein through two independent binding motifs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
10. [The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
11. [Molecular composition of IMP1 ribonucleoprotein granules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
12. [Translational repression by a novel partner of human poly(A) binding protein, Paip2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
13. [The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
14. [Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
15. [Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
16. [The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
17. [Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
18. [MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
19. [The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
20. [Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
21. [Both G3BP1 and G3BP2 contribute to stress granule formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
22. [Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
23. [DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
24. [The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
25. [Insulin receptor substrate-1 (IRS-1) forms a ribonucleoprotein complex associated with polysomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
26. [Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
27. [Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
28. [Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
29. [Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
30. [Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
31. [Assembly of AUF1 with eIF4G-poly(A) binding protein complex suggests a translation function in AU-rich mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
32. [Recognition of eIF4G by rotavirus NSP3 reveals a basis for mRNA circularization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
33. [eIF4E-bound mRNPs are substrates for nonsense-mediated mRNA decay in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
34. [An integrative approach to gain insights into the cellular function of human ataxin-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
35. [Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
36. [Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
37. [Quantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
38. [Molecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
39. [Poly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
40. [A mechanism of translational repression by competition of Paip2 with eIF4G for poly(A) binding protein (PABP) binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
41. [A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
42. [A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
43. [Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
44. [GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
45. [Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
46. [Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
47. [Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
48. [Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
49. [Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)
50. [Regulation of poly(A) binding protein function in translation: Characterization of the Paip2 homolog, Paip2B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11940)