# Polo like kinase 4

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109157](https://www.wikidata.org/wiki/Q21109157)  
**Source**: https://4ort.xyz/entity/polo-like-kinase-4


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O00444)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
6. [Sak kinase gene structure and transcriptional regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444)
8. [KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444)
9. [The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444)
10. [Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
11. [The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
12. [KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
13. [Asterless is a scaffold for the onset of centriole assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
14. [Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
15. [Plk4 is required for cytokinesis and maintenance of chromosomal stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
16. [STIL binding to Polo-box 3 of PLK4 regulates centriole duplication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
17. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
18. [Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
19. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
20. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
21. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
22. [A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
23. [Pooled-matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
24. [Sak kinase gene structure and transcriptional regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
25. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
26. [Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444)
27. [The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444)
28. [Plk4-induced centriole biogenesis in human cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444)
29. [The Polo kinase Plk4 functions in centriole duplication](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444)
30. [Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
31. [The Polo kinase Plk4 functions in centriole duplication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
32. [Plk4-induced centriole biogenesis in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
33. [The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
34. [STIL is required for centriole duplication in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444)
35. Ensembl Release 99
36. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)