# plicamycin

> antibiotic isolated from the bacterium Streptomyces plicatus with antineoplastic activity

**Wikidata**: [Q3906700](https://www.wikidata.org/wiki/Q3906700)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Plicamycin)  
**Source**: https://4ort.xyz/entity/plicamycin


## References

1. Plicamycin. DrugBank. 2015
2. [CAS Common Chemistry](https://commonchemistry.cas.org/detail?cas_rn=18378-89-7)
3. (1S)-5-Deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-b-D-arabino-hexopyranosyl)-b-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-b-D-ribo-hexopyranosyl-(1.fwdarw.3)-O-2,6-dideoxy-b-D-lyxo-hexopyranosyl-(1.fwdarw.3)-2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose. ECHA Substance Infocard database
4. CHEMBL1237054. PubChem
5. PubChem
6. Natural Product Atlas
7. ChEBI release 2020-09-01
8. Medical Subject Headings
9. PLICAMYCIN. ChEMBL
10. IUPHAR/BPS Guide to PHARMACOLOGY
11. PLICAMYCIN. NDF-RT
12. (1S)-5-Deoxy-1-C-[(2S,3S)-7-{[2,6-dideoxy-3-O-(2,6-dideoxy-alpha-D-arabino-hexopyranosyl)-beta-D-arabino-hexopyranosyl]oxy}-3-{[2,6-dideoxy-3-C-methyl-alpha-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-alp. ChemSpider
13. Plicamycin. ChEMBL
14. Hybrid compounds generated by the introduction of a nogalamycin-producing plasmid into Streptomyces argillaceus
15. Two novel C-glycosides of aureolic acid repress transcription of the MDR1 gene
16. The Structure of Mithramycin Reinvestigated
17. Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin
18. Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches
19. Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus
20. Increased heterologous production of the antitumoral polyketide mithramycin A by engineered Streptomyces lividans TK24 strains
21. NDF-RT
22. [Source](http://echa.europa.eu/de/information-on-chemicals/registered-substances)
23. UMLS 2023
24. UniChem