# Pleiotrophin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q14916157](https://www.wikidata.org/wiki/Q14916157)  
**Source**: https://4ort.xyz/entity/pleiotrophin-q14916157


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P21246)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21246)
5. [Pleiotrophin signals increased tyrosine phosphorylation of β-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase β/ζ](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21246)
6. [A heparin-binding growth factor secreted from breast cancer cells homologous to a developmentally regulated cytokine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21246)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21246&geneProductId=UniProtKB:P21246)
8. [A heparin-binding growth factor secreted from breast cancer cells homologous to a developmentally regulated cytokine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21246&geneProductId=UniProtKB:P21246)
9. [Structural studies reveal an important role for the pleiotrophin C‐terminus in mediating interactions with chondroitin sulfate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21246)
10. [Characterization of hNek6 Interactome Reveals an Important Role for Its Short N-Terminal Domain and Colocalization with Proteins at the Centrosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21246)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21246)
12. [Cloning and Expression of a Developmentally Regulated Protein That Induces Mitogenic and Neurite Outgrowth Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21246)
13. Ensembl Release 99