Platelet factor 4
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P361
  value: platelet factor 4
additional property: PropertyValue
  property ID: P361
  value: Chemokine interleukin-8-like superfamily
additional property: PropertyValue
  property ID: P361
  value: Chemokine interleukin-8-like domain, protein family
additional property: PropertyValue
  property ID: P527
  value: CXC chemokine, conserved site
additional property: PropertyValue
  property ID: P527
  value: Chemokine interleukin-8-like domain
additional property: PropertyValue
  property ID: P527
  value: CXC Chemokine domain
additional property: PropertyValue
  property ID: P637
  value: NP_064316
additional property: PropertyValue
  property ID: P680
  value: cytokine activity
additional property: PropertyValue
  property ID: P680
  value: heparin binding
additional property: PropertyValue
  property ID: P680
  value: CXCR3 chemokine receptor binding
additional property: PropertyValue
  property ID: P681
  value: extracellular region
additional property: PropertyValue
  property ID: P681
  value: extracellular space
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P682
  value: G protein-coupled receptor signaling pathway
additional property: PropertyValue
  property ID: P682
  value: cytokine-mediated signaling pathway
additional property: PropertyValue
  property ID: P682
  value: chemokine-mediated signaling pathway
additional property: PropertyValue
  property ID: P702
  value: Pf4
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000031320
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000143818
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 8
      unique citations norm: 0.003
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 8
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9Z126
    source count: 1
    confidence: 0.2
  P361:
    value: Q24772397
    source count: 1
    confidence: 0.2
    value label: platelet factor 4
  P361:
    value: Q41797185
    source count: 1
    confidence: 0.2
    value label: Chemokine interleukin-8-like superfamily
  P361:
    value: Q83139055
    source count: 1
    confidence: 0.2
    value label: Chemokine interleukin-8-like domain, protein family
  P361:
    value: Q83167084
    source count: 1
    confidence: 0.2
    value label: CXC Chemokine domain, protein family
  P361:
    value: Q95353681
    source count: 1
    confidence: 0.2
    value label: CXC chemokine, conserved site, protein family
  P527:
    value: Q24776582
    source count: 1
    confidence: 0.2
    value label: CXC chemokine, conserved site
  P527:
    value: Q24767885
    source count: 1
    confidence: 0.2
    value label: Chemokine interleukin-8-like domain
  P527:
    value: Q27185374
    source count: 1
    confidence: 0.2
    value label: CXC Chemokine domain
  P637:
    value: NP_064316
    source count: 1
    confidence: 0.2
  P680:
    value: Q14862699
    source count: 1
    confidence: 0.2
    value label: cytokine activity
  P680:
    value: Q14819453
    source count: 5
    confidence: 1.0
    value label: heparin binding
  P680:
    value: Q14907862
    source count: 2
    confidence: 0.4
    value label: CXCR3 chemokine receptor binding
  P680:
    value: Q14875871
    source count: 2
    confidence: 0.4
    value label: chemokine activity
  P680:
    value: Q21095651
    source count: 1
    confidence: 0.2
    value label: CXCR chemokine receptor binding
  P681:
    value: Q14645596
    source count: 2
    confidence: 0.4
    value label: extracellular region
  P681:
    value: Q1385443
    source count: 2
    confidence: 0.4
    value label: extracellular space
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q14905221
    source count: 1
    confidence: 0.2
    value label: symbiont-containing vacuole membrane
  P681:
    value: Q14863673
    source count: 2
    confidence: 0.4
    value label: platelet alpha granule
  P682:
    value: Q14758909
    source count: 1
    confidence: 0.2
    value label: G protein-coupled receptor signaling pathway
  P682:
    value: Q14863107
    source count: 2
    confidence: 0.4
    value label: cytokine-mediated signaling pathway

value: Q14864360
source count: 1
confidence: 0.2
value label: chemokine-mediated signaling pathway

value: Q14860513
source count: 1
confidence: 0.2
value label: positive regulation of macrophage differentiation

value: Q14905358
source count: 2
confidence: 0.4
value label: negative regulation of megakaryocyte differentiation

value: Q14905360
source count: 1
confidence: 0.2
value label: Pf4

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000031320
source count: 1
confidence: 0.2

value: ENSMUSP00000143818
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-07-16

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices
stated in qid: Q35878774
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q14905361
domain: protein
level: standard
html url: https://4ort.xyz/entity/platelet-factor-4-q14905361
markdown url: https://4ort.xyz/entity/platelet-factor-4-q14905361.md
facts url summary: https://4ort.xyz/entity/platelet-factor-4-q14905361/facts.json
facts url standard: https://4ort.xyz/entity/platelet-factor-4-q14905361/facts.json
facts url full: https://4ort.xyz/entity/platelet-factor-4-q14905361/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T08:41:31.577209Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:38:59.049836+00:00Z