# Platelet derived growth factor receptor beta

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21108624](https://www.wikidata.org/wiki/Q21108624)  
**Source**: https://4ort.xyz/entity/platelet-derived-growth-factor-receptor-beta-q21108624


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL502835)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL941)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1908391)
6. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1201556)
7. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1278146)
8. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL274654)
9. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL49120)
10. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL124660)
11. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1642)
12. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P09619)
13. Q20641742
14. [Vascular endothelial growth factor can signal through platelet-derived growth factor receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
16. [Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09619&geneProductId=UniProtKB:P09619)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09619&geneProductId=UniProtKB:P09619)
18. [Site-selective dephosphorylation of the platelet-derived growth factor beta-receptor by the receptor-like protein-tyrosine phosphatase DEP-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
19. [Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09619&geneProductId=UniProtKB:P09619)
20. [cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09619&geneProductId=UniProtKB:P09619)
21. [Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
22. [Two different subunits associate to create isoform-specific platelet-derived growth factor receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
23. [NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
24. [Binding of GAP to activated PDGF receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
25. [PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
26. [PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
27. [Structural and Thermodynamic Basis for the Interaction of the Src SH2 Domain with the Activated Form of the PDGF β-receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
28. [In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
29. [Protein tyrosine phosphatase 1B interacts with and is tyrosine phosphorylated by the epidermal growth factor receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
30. [Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
31. [Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
32. [Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
33. [Identification of protein tyrosine phosphatases associating with the PDGF receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
34. [Alternative modes of binding of proteins with tandem SH2 domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
35. [Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
36. [Dual specificity of Src homology 2 domains for phosphotyrosine peptide ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
37. [Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
38. [GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
39. [Wild-type LRP6 inhibits, whereas atherosclerosis-linked LRP6R611C increases PDGF-dependent vascular smooth muscle cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
40. [The BPV-1 E5 protein, the 16 kDa membrane pore-forming protein and the PDGF receptor exist in a complex that is dependent on hydrophobic transmembrane interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
41. [Synergistic roles of platelet-derived growth factor-BB and interleukin-1beta in phenotypic modulation of human aortic smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
42. [NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
43. [Src-like adaptor protein (Slap) is a negative regulator of mitogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
44. [Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
45. [A biosensor approach to probe the structure and function of the p85 alpha subunit of the phosphatidylinositol 3-kinase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
46. [Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
47. [Breast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
48. [Platelet-derived growth factor receptor sequences important for binding of src family tyrosine kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
49. [Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)
50. [Large-scale structural analysis of the classical human protein tyrosine phosphatome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09619)