# Platelet derived growth factor receptor, alpha polypeptide

> mammalian protein found in Mus musculus

**Wikidata**: [Q21988893](https://www.wikidata.org/wiki/Q21988893)  
**Source**: https://4ort.xyz/entity/platelet-derived-growth-factor-receptor-alpha-polypeptide


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P26618)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26618&geneProductId=UniProtKB:P26618)
6. [A Reactive Oxygen Species-Mediated, Self-Perpetuating Loop Persistently Activates Platelet-Derived Growth Factor Receptor α](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
7. [Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26618&geneProductId=UniProtKB:P26618)
8. [Abnormal development of NG2+PDGFR-α+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
9. [Epicardial–Myocardial Signaling Directing Coronary Vasculogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26618&geneProductId=UniProtKB:P26618)
10. [Tissue plasminogen activator is a potent activator of PDGF-CC](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26618&geneProductId=UniProtKB:P26618)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26618&geneProductId=UniProtKB:P26618)
12. [Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
14. [Epicardial–Myocardial Signaling Directing Coronary Vasculogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
15. [Tissue plasminogen activator is a potent activator of PDGF-CC](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
16. [Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
17. [Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
18. [An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
19. [The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
20. [Role of Scaffold Protein Afadin Dilute Domain-interacting Protein (ADIP) in Platelet-derived Growth Factor-induced Cell Movement by Activating Rac Protein through Vav2 Protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
21. [Role of Scaffold Protein Afadin Dilute Domain-interacting Protein (ADIP) in Platelet-derived Growth Factor-induced Cell Movement by Activating Rac Protein through Vav2 Protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26618&geneProductId=UniProtKB:P26618)
22. [IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26618&geneProductId=UniProtKB:P26618)
23. [IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
24. [Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
25. [The PDGF signaling pathway controls multiple steroid-producing lineages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
26. [The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
27. [PDGFR-alpha signaling is critical for tooth cusp and palate morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
28. [PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
29. [Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
30. [PDGF signaling specificity is mediated through multiple immediate early genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
31. [PDGF-A/PDGF alpha-receptor signaling is required for lung growth and the formation of alveoli but not for early lung branching morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
32. [ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
33. [Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
34. [Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26618&geneProductId=UniProtKB:P26618)
35. [The PDGFα receptor is required for neural crest cell development and for normal patterning of the somites](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
36. [Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
37. [The PDGFα receptor is required for neural crest cell development and for normal patterning of the somites](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26618&geneProductId=UniProtKB:P26618)
38. [Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26618)
39. ensembl Release 106