Piwi-like RNA-mediated gene silencing 1
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Ribonuclease H superfamily
additional property: PropertyValue
  property ID: P361
  value: PAZ domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Ribonuclease H-like superfamily
additional property: PropertyValue
  property ID: P527
  value: Argonaute, linker 1 domain
additional property: PropertyValue
  property ID: P527
  value: Piwi domain
additional property: PropertyValue
  property ID: P527
  value: PAZ domain
additional property: PropertyValue
  property ID: P637
  value: NP_067286
additional property: PropertyValue
  property ID: P637
  value: XP_006504381
additional property: PropertyValue
  property ID: P638
  value: 2XFM
additional property: PropertyValue
  property ID: P638
  value: 4P1Z
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P680
  value: single-stranded RNA binding
additional property: PropertyValue
  property ID: P680
  value: RNA binding
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: chromatoid body
additional property: PropertyValue
  property ID: P681
  value: polysome
additional property: PropertyValue
  property ID: P682
  value: cell differentiation
additional property: PropertyValue
  property ID: P682
  value: multicellular organism development
additional property: PropertyValue
  property ID: P682
  value: meiosis
additional property: PropertyValue
  property ID: P702
  value: Piwil1
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000083222
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000142386
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000142807
confidence:
  popularity graph score:
    score: 0.004
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 28
      unique citations norm: 0.011
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 28
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9JMB7
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797512
    source count: 1
    confidence: 0.2
    value label: Ribonuclease H superfamily
  P361:
    value: Q41797219
    source count: 1
    confidence: 0.2
    value label: PAZ domain superfamily
  P361:
    value: Q24720586
    source count: 1
    confidence: 0.2
    value label: Ribonuclease H-like superfamily
  P361:
    value: Q24738695
    source count: 1
    confidence: 0.2
    value label: Piwi-like protein 1
  P361:
    value: Q83140985
    source count: 1
    confidence: 0.2
    value label: Piwi domain, protein family
  P527:
    value: Q24722780
    source count: 1
    confidence: 0.2
    value label: Argonaute, linker 1 domain
  P527:
    value: Q24773232
    source count: 1
    confidence: 0.2
    value label: Piwi domain
  P527:
    value: Q24778536
    source count: 1
    confidence: 0.2
    value label: PAZ domain
  P527:
    value: Q24725722
    source count: 1
    confidence: 0.2
    value label: GAGE
  P637:
    value: NP_067286
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006504381
    source count: 1
    confidence: 0.2
  P638:
    value: 2XFM
    source count: 1
    confidence: 0.2
  P638:
    value: 4P1Z
    source count: 1
    confidence: 0.2
  P680:
    value: Q167149
    source count: 13
    confidence: 1.0
    value label: protein binding
  P680:
    value: Q14908224
    source count: 2
    confidence: 0.4
    value label: single-stranded RNA binding
  P680:
    value: Q14330639
    source count: 1
    confidence: 0.2
    value label: RNA binding
  P680:
    value: Q14864825
    source count: 1
    confidence: 0.2
    value label: nucleic acid binding
  P680:
    value: Q14633859
    source count: 2
    confidence: 0.4
    value label: mRNA binding
  P681:
    value: Q79899
    source count: 8
    confidence: 1.0
    value label: cytoplasm

value: Q18347550
source count: 3
confidence: 0.6
value label: chromatoid body

value: Q970614
source count: 1
confidence: 0.2
value label: polysome

value: Q220599
source count: 1
confidence: 0.2
value label: cytosol

value: Q14882306
source count: 1
confidence: 0.2
value label: mRNA cap binding complex

value: Q210861
source count: 1
confidence: 0.2
value label: cell differentiation

value: Q14645705
source count: 1
confidence: 0.2
value label: multicellular organism development

value: Q16424695
source count: 1
confidence: 0.2
value label: meiosis

value: Q1431332
source count: 2
confidence: 0.4
value label: gene silencing

value: Q14863717
source count: 2
confidence: 0.4
value label: regulation of translation

value: Q18258774
source count: 1
confidence: 0.2
value label: Piwil1

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000083222
source count: 1
confidence: 0.2

value: ENSMUSP00000142386
source count: 1
confidence: 0.2

value: ENSMUSP00000142807
source count: 1
confidence: 0.2

source: Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells
stated in qid: Q28507218
retrieved: 2019-02-14

source: Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis.
stated in qid: Q32874809
retrieved: 2019-02-14

source: Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression
stated in qid: Q28593820
retrieved: 2019-02-14

source: MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis
stated in qid: Q28511905
retrieved: 2019-02-14

source: Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression
stated in qid: Q40036323
retrieved: 2019-02-14

source: Circadian proteins CLOCK and BMAL1 in the chromatoid body, a RNA processing granule of male germ cells
stated in qid: Q28591085
retrieved: 2019-02-14

source: Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway
stated in qid: Q28586946
retrieved: 2019-02-14

source: piRNA-Triggered MIWI Ubiquitination and Removal by APC/C in Late Spermatogenesis
stated in qid: Q32874774
retrieved: 2019-02-14

source: GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline
stated in qid: Q28589716
retrieved: 2019-02-14

source: Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline
stated in qid: Q28588151
retrieved: 2019-02-14

source: Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?
stated in qid: Q28507866
retrieved: 2019-02-14

source: Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain
stated in qid: Q24615547
retrieved: 2019-02-14

source: Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi
stated in qid: Q27658209
retrieved: 2019-02-14

source: miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis
stated in qid: Q28589737
retrieved: 2019-02-14

source: Two mouse piwi-related genes: miwi and mili
stated in qid: Q28584745
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: STK31(TDRD8) is dynamically regulated throughout mouse spermatogenesis and interacts with MIWI protein
stated in qid: Q28509323
retrieved: 2019-02-14

source: Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing
stated in qid: Q28854369
retrieved: 2019-02-14

source: A novel class of small RNAs in mouse spermatogenic cells
stated in qid: Q28593537
retrieved: 2019-02-14

source: A germline-specific class of small RNAs binds mammalian Piwi proteins
stated in qid: Q28244097
retrieved: 2019-02-14

source: MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis
stated in qid: Q28511905
retrieved: 2018-09-10

source: Mouse ZAR1-like (XM_359149) colocalizes with mRNA processing components and its dominant-negative mutant caused two-cell-stage embryonic arrest
stated in qid: Q22001539
retrieved: 2019-02-14

source: Mili, a mammalian member of piwi family gene, is essential for spermatogenesis
stated in qid: Q28585613
retrieved: 2019-02-14

source: Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse
stated in qid: Q28508286
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21989904
domain: protein
level: standard
html url: https://4ort.xyz/entity/piwi-like-rna-mediated-gene-silencing-1-q21989904
markdown url: https://4ort.xyz/entity/piwi-like-rna-mediated-gene-silencing-1-q21989904.md
facts url summary: https://4ort.xyz/entity/piwi-like-rna-mediated-gene-silencing-1-q21989904/facts.json
facts url standard: https://4ort.xyz/entity/piwi-like-rna-mediated-gene-silencing-1-q21989904/facts.json
facts url full: https://4ort.xyz/entity/piwi-like-rna-mediated-gene-silencing-1-q21989904/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-06T00:04:49.198948Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:25:40.090227+00:00Z