# Pim-2 proto-oncogene, serine/threonine kinase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21123752](https://www.wikidata.org/wiki/Q21123752)  
**Source**: https://4ort.xyz/entity/pim-2-proto-oncogene-serine-threonine-kinase


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1952329)
4. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9P1W9)
5. Q20641742
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P1W9)
7. [The human Pim-2 proto-oncogene and its testicular expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P1W9&geneProductId=UniProtKB:Q9P1W9)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P1W9&geneProductId=UniProtKB:Q9P1W9)
9. [Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P1W9&geneProductId=UniProtKB:Q9P1W9)
10. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P1W9)
11. [The human Pim-2 proto-oncogene and its testicular expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P1W9)
12. [Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P1W9)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P1W9)
14. [Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P1W9)
15. [Serine/threonine kinase Pim-2 promotes liver tumorigenesis induction through mediating survival and preventing apoptosis of liver cell](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P1W9)
16. [Pim-2 phosphorylation of p21Cip1/WAF1 enhances its stability and inhibits cell proliferation in HCT116 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P1W9)
17. Ensembl Release 99