Phospholipase D1
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P70496
additional property: PropertyValue
  property ID: P361
  value: PX domain superfamily
additional property: PropertyValue
  property ID: P361
  value: PH-like domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Phospholipase D, eukaryotic type
additional property: PropertyValue
  property ID: P527
  value: Phospholipase D/Transphosphatidylase
additional property: PropertyValue
  property ID: P527
  value: pleckstrin homology domain
additional property: PropertyValue
  property ID: P527
  value: Phox homologous domain
additional property: PropertyValue
  property ID: P637
  value: NP_112254
additional property: PropertyValue
  property ID: P637
  value: XP_006232267
additional property: PropertyValue
  property ID: P637
  value: XP_006232268
additional property: PropertyValue
  property ID: P680
  value: catalytic activity
additional property: PropertyValue
  property ID: P680
  value: phospholipase D activity
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P681
  value: Golgi membrane
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: endosome
additional property: PropertyValue
  property ID: P682
  value: lipid metabolism
additional property: PropertyValue
  property ID: P682
  value: phosphatidic acid biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: phospholipid biosynthetic process
additional property: PropertyValue
  property ID: P702
  value: Pld1
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000034466
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000035045
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 13
      unique citations norm: 0.005
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 13
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P70496
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797967
    source count: 1
    confidence: 0.2
    value label: PX domain superfamily
  P361:
    value: Q24786013
    source count: 1
    confidence: 0.2
    value label: PH-like domain superfamily
  P361:
    value: Q41796592
    source count: 1
    confidence: 0.2
    value label: Phospholipase D, eukaryotic type
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83145268
    source count: 1
    confidence: 0.2
    value label: pleckstrin homology domain, protein family
  P527:
    value: Q24778865
    source count: 1
    confidence: 0.2
    value label: Phospholipase D/Transphosphatidylase
  P527:
    value: Q24776397
    source count: 1
    confidence: 0.2
    value label: pleckstrin homology domain
  P527:
    value: Q24779779
    source count: 1
    confidence: 0.2
    value label: Phox homologous domain
  P527:
    value: Q24773010
    source count: 1
    confidence: 0.2
    value label: Phospholipase D-like domain
  P637:
    value: NP_112254
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006232267
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006232268
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001386011
    source count: 1
    confidence: 0.2
  P680:
    value: Q1735592
    source count: 1
    confidence: 0.2
    value label: catalytic activity
  P680:
    value: Q14882853
    source count: 3
    confidence: 0.6
    value label: phospholipase D activity
  P680:
    value: Q167149
    source count: 1
    confidence: 0.2
    value label: protein binding
  P680:
    value: Q14353168
    source count: 1
    confidence: 0.2
    value label: hydrolase activity
  P680:
    value: Q14886045
    source count: 1
    confidence: 0.2
    value label: phosphatidylinositol binding
  P681:
    value: Q14598778
    source count: 1
    confidence: 0.2
    value label: Golgi membrane
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q824237
    source count: 1
    confidence: 0.2
    value label: endosome

value: Q79927
source count: 1
confidence: 0.2
value label: endoplasmic reticulum

value: Q14329032
source count: 1
confidence: 0.2
value label: endoplasmic reticulum membrane

value: Q2792936
source count: 1
confidence: 0.2
value label: lipid metabolism

value: Q21103181
source count: 2
confidence: 0.4
value label: phosphatidic acid biosynthetic process

value: Q14905002
source count: 1
confidence: 0.2
value label: phospholipid biosynthetic process

value: Q21097228
source count: 1
confidence: 0.2
value label: phospholipid catabolic process

value: Q14762268
source count: 1
confidence: 0.2
value label: lipid catabolic process

value: Q24395537
source count: 1
confidence: 0.2
value label: Pld1

value: Q184224
source count: 1
confidence: 0.2
value label: brown rat

value: ENSRNOP00000034466
source count: 1
confidence: 0.2

value: ENSRNOP00000035045
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Mechanisms of regulation of phospholipase D1 by protein kinase Calpha
stated in qid: Q28583029
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Phospholipase D is essential for keratocyte-like migration of NBT-II cells
stated in qid: Q28771336
retrieved: 2019-02-14

source: Phospholipase D2 is localized to the rims of the Golgi apparatus in mammalian cells
stated in qid: Q28567228
retrieved: 2019-02-14

source: Subcellular distribution and characterization of rat pancreatic phospholipase D isoforms
stated in qid: Q28570935
retrieved: 2019-02-14

source: A role for phospholipase D1 in neurotransmitter release.
stated in qid: Q33953145
retrieved: 2019-02-14

source: P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis
stated in qid: Q28510364
retrieved: 2019-02-14

source: Parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells
stated in qid: Q28574700
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q28556577
domain: protein
level: standard
html url: https://4ort.xyz/entity/phospholipase-d1
markdown url: https://4ort.xyz/entity/phospholipase-d1.md
facts url summary: https://4ort.xyz/entity/phospholipase-d1/facts.json
facts url standard: https://4ort.xyz/entity/phospholipase-d1/facts.json
facts url full: https://4ort.xyz/entity/phospholipase-d1/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T20:12:58.219366Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:48:25.631733+00:00Z