# Phosphodiesterase 5A

> mammalian protein found in Homo sapiens

**Wikidata**: [Q410798](https://www.wikidata.org/wiki/Q410798)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/CGMP-specific_phosphodiesterase_type_5)  
**Source**: https://4ort.xyz/entity/phosphodiesterase-5a


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL192)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL19449)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1928262)
6. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O76074)
7. Q20641742
8. Freebase Data Dumps. 2013
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76074)
10. [Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding, cGMP-specific 3′,5′-cyclic nucleotide phosphodiesterase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76074)
11. [Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system](http://www.ebi.ac.uk/QuickGO/annotations?protein=O76074&geneProductId=UniProtKB:O76074)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O76074&geneProductId=UniProtKB:O76074)
13. [Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76074)
14. [Differentiation of human monocytes in vitro with granulocyte-macrophage colony-stimulating factor and macrophage colony-stimulating factor produces distinct changes in cGMP phosphodiesterase expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=O76074&geneProductId=UniProtKB:O76074)
15. [Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76074)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76074)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=O76074&geneProductId=UniProtKB:O76074)
18. [Differentiation of human monocytes in vitro with granulocyte-macrophage colony-stimulating factor and macrophage colony-stimulating factor produces distinct changes in cGMP phosphodiesterase expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76074)
19. Ensembl Release 99
20. Identifiers.org
21. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)