# Phosphodiesterase 5A, cGMP-specific

> mammalian protein found in Mus musculus

**Wikidata**: [Q14865589](https://www.wikidata.org/wiki/Q14865589)  
**Source**: https://4ort.xyz/entity/phosphodiesterase-5a-cgmp-specific


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8CG03)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CG03)
5. [Cyclic GMP signaling is involved in the luteinizing hormone-dependent meiotic maturation of mouse oocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CG03)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CG03&geneProductId=UniProtKB:Q8CG03)
7. [PDE5 is converted to an activated state upon cGMP binding to the GAF A domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CG03&geneProductId=UniProtKB:Q8CG03)
8. [Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: INSIGHTS INTO NUCLEOTIDE SPECIFICITY, DIMERIZATION, AND cGMP-DEPENDENT CONFORMATIONAL CHANGE](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CG03&geneProductId=UniProtKB:Q8CG03)
9. [PDE5 is converted to an activated state upon cGMP binding to the GAF A domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CG03)
10. [Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: INSIGHTS INTO NUCLEOTIDE SPECIFICITY, DIMERIZATION, AND cGMP-DEPENDENT CONFORMATIONAL CHANGE](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CG03)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CG03)
12. [Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CG03)
13. [The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CG03)
14. [Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CG03)
15. [Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CG03)
16. ensembl Release 106