# Phosphodiesterase 4D

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28560283](https://www.wikidata.org/wiki/Q28560283)  
**Source**: https://4ort.xyz/entity/phosphodiesterase-4d-q28560283


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P14270)
3. Q20641742
4. [Cloning and characterization of novel PDE4D isoforms PDE4D6 and PDE4D7](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
7. [Myomegalin is a novel protein of the golgi/centrosome that interacts with a cyclic nucleotide phosphodiesterase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
8. [Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
9. [β1‐adrenergic receptor antagonists signal via PDE4 translocation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
10. [Prolyl hydroxylase domain protein 2 regulates the intracellular cyclic AMP level in cardiomyocytes through its interaction with phosphodiesterase 4D](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
11. [Differential association of phosphodiesterase 4D isoforms with beta2-adrenoceptor in cardiac myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
12. [Spectrin-anchored phosphodiesterase 4D4 restricts cAMP from disrupting microtubules and inducing endothelial cell gap formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
13. [mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
14. [GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
15. [The induction of cyclic nucleotide phosphodiesterase 4 gene (PDE4D) impairs memory in a water maze task](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
16. [beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
17. [Lentiviral-Mediated shRNA Silencing of PDE4D Gene Inhibits Platelet-Derived Growth Factor-Induced Proliferation and Migration of Rat Aortic Smooth Muscle Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
18. [Differential expression of cyclic nucleotide phosphodiesterases 4 in developing rat lung](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
19. [Intrinsic sex-specific differences in microvascular endothelial cell phosphodiesterases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14270)
20. ensembl Release 104