mammalian protein found in Rattus norvegicus
Bifunctional phosphatidylinositol trisphosphate phosphatase/dual specificity phosphatase PTEN
Tensin phosphatase, C2 domain, protein family
Protein-tyrosine phosphatase, active site
phosphatidylinositol-3-phosphatase activity
protein serine/threonine phosphatase activity
negative regulation of protein phosphorylation
Tensin-type phosphatase domain, protein family
platelet-derived growth factor receptor binding
Inactivation of platelet-derived growth factor receptor by the tumor suppressor PTEN provides a novel mechanism of action of the phosphatase
Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment
PDZ domains of Par-3 as potential phosphoinositide signaling integrators
Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse
Phosphorylation of the actin binding protein Drebrin at S647 is regulated by neuronal activity and PTEN
PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression
PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid--mechanistic analysis of a familial Cowden disease-associated PTEN mutation
Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN.
Beta1-adrenergic receptors promote focal adhesion signaling downregulation and myocyte apoptosis in acute volume overload
Critical role of PTEN in the coupling between PI3K/Akt and JNK1/2 signaling in ischemic brain injury
PTEN: a crucial mediator of mitochondria-dependent apoptosis
A role for nuclear PTEN in neuronal differentiation.
PTEN recruitment controls synaptic and cognitive function in Alzheimer's models.
Aging gastropathy-novel mechanisms: hypoxia, up-regulation of multifunctional phosphatase PTEN, and proapoptotic factors
Age-dependent expression of Pten and Smad4 genes in the urogenital system of Wistar rats
In utero exposure to maternal diets containing soy protein isolate, but not genistein alone, protects young adult rat offspring from NMU-induced mammary tumorigenesis
The involvement of PTEN in sleep deprivation-induced memory impairment in rats
Perlecan-induced suppression of smooth muscle cell proliferation is mediated through increased activity of the tumor suppressor PTEN
Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN
Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs
Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway
Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells
Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis
Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway
Inhibition of neuronal phenotype by PTEN in PC12 cells
17 Beta-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats
Ethanol impairs insulin-stimulated neuronal survival in the developing brain: role of PTEN phosphatase
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
AMPK regulates K(ATP) channel trafficking via PTEN inhibition in leptin-treated pancreatic β-cells