Bifunctional phosphatidylinositol trisphosphate phosphatase/dual specificity phosphatase PTEN
Tensin phosphatase, C2 domain, protein family
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
negative regulation of cell population proliferation
Tensin-type phosphatase domain, protein family
Protein-tyrosine phosphatase, catalytic domain, protein family
Protein-tyrosine phosphatase, active site
protein serine/threonine phosphatase activity
Regulation of PTEN Stability and Activity by Plk3
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells
PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling
Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination
PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression
Involvement of PTEN in TPA‐mediated p53‐activation in mouse skin epidermal JB6 cells
Essential role for nuclear PTEN in maintaining chromosomal integrity
The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network
Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis
The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves
Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain
Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2
Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression
Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities
Pten knockdown in vivo increases excitatory drive onto dentate granule cells
Pten regulates neuronal arborization and social interaction in mice
Haploinsufficiency for Pten and Serotonin transporter cooperatively influences brain size and social behavior
MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue
PTEN degradation after ischemic stroke: a double-edged sword
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
Analysis of mouse embryonic patterning and morphogenesis by forward genetics
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility
Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury
A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice