# PHD finger protein 8

> mammalian protein found in Homo sapiens

**Wikidata**: [Q22683566](https://www.wikidata.org/wiki/Q22683566)  
**Source**: https://4ort.xyz/entity/phd-finger-protein-8-q22683566


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UPP1)
4. Q20641742
5. [Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPP1)
6. [Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPP1)
7. [PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPP1)
8. [PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPP1)
9. [A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPP1)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPP1)
11. [Nucleosome-interacting proteins regulated by DNA and histone methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPP1)
12. [NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPP1)
13. [PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPP1)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UPP1&geneProductId=UniProtKB:Q9UPP1)
15. Ensembl Release 99