# Peroxisome proliferator activated receptor gamma

> mammalian protein found in Homo sapiens

**Wikidata**: [Q1084878](https://www.wikidata.org/wiki/Q1084878)  
**Source**: https://4ort.xyz/entity/peroxisome-proliferator-activated-receptor-gamma


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P37231)
4. Q20641742
5. Freebase Data Dumps. 2013
6. [Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
7. [Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
8. [Retinoid-dependent recruitment of a histone H1 displacement activity by retinoic acid receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
9. [Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
10. [Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
11. [A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
12. [Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
13. [Huntingtin interacting proteins are genetic modifiers of neurodegeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
14. [SIRT1 is regulated by a PPAR{γ}-SIRT1 negative feedback loop associated with senescence](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
15. [The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
17. [Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
19. [Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
20. [Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
21. [PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
22. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
23. [Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
24. [Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
25. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
26. [Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
27. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
28. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
29. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
30. [Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
31. [PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
32. [Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
33. [Peroxisome proliferator-activated receptor gamma activates fas ligand gene promoter inducing apoptosis in human breast cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
34. [Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
35. [Molecular mechanisms underlying the inhibition of IFN-γ-induced, STAT1-mediated gene transcription in human macrophages by simvastatin and agonists of PPARs and LXRs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
36. [PPARα and PPARγ activators suppress the monocyte-macrophage apoB-48 receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
37. [PPAR and LXR activators regulate ABCA12 expression in human keratinocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
38. [Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
39. [Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR alpha and PPAR gamma-dependent pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
40. [Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
41. [Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
42. [The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
43. [PPARα and PPARγ activators suppress the monocyte-macrophage apoB-48 receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
44. [Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
45. [Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR alpha and PPAR gamma-dependent pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
46. [Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
47. [PPAR and LXR activators regulate ABCA12 expression in human keratinocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231)
48. [A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
49. [Peroxisome proliferator-activated receptor-γ enhances human pulmonary artery smooth muscle cell apoptosis through microRNA-21 and programmed cell death 4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)
50. [Hypoxia Mediates Mutual Repression between microRNA-27a and PPARγ in the Pulmonary Vasculature](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231)