# Peroxisome proliferator activated receptor alpha

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7169506](https://www.wikidata.org/wiki/Q7169506)  
**Source**: https://4ort.xyz/entity/peroxisome-proliferator-activated-receptor-alpha


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q07869)
4. Q20641742
5. [Differences in the formation of PPARalpha-RXR/acoPPRE complexes between responsive and nonresponsive species upon fibrate administration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
7. [SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
8. [The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein A-I expression by fibrates](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
9. [The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein A-I expression by fibrates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
10. [Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
11. [Interaction of hepatitis C virus core protein with retinoid X receptor alpha modulates its transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
12. [The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
13. [SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
14. [Structural Basis for Iloprost as a Dual Peroxisome Proliferator-activated Receptor  /  Agonist](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
15. [PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
16. [Phospho-tyrosine dependent protein-protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
18. [Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
19. [Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
20. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
22. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
24. [Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
25. [An intronic peroxisome proliferator-activated receptor-binding sequence mediates fatty acid induction of the human carnitine palmitoyltransferase 1A](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
26. [MicroRNA-518d regulates PPARα protein expression in the placentas of females with gestational diabetes mellitus](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
27. [An intronic peroxisome proliferator-activated receptor-binding sequence mediates fatty acid induction of the human carnitine palmitoyltransferase 1A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
28. [MicroRNA-518d regulates PPARα protein expression in the placentas of females with gestational diabetes mellitus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
29. [MicroRNA-21 targets peroxisome proliferators-activated receptor-α in an autoregulatory loop to modulate flow-induced endothelial inflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
30. [cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
31. [Peroxisome Proliferator-activated Receptor α-Isoform Deficiency Leads to Progressive Dyslipidemia with Sexually Dimorphic Obesity and Steatosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
32. [PPARα and PPARγ activators suppress the monocyte-macrophage apoB-48 receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
33. [A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
34. [Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR alpha and PPAR gamma-dependent pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
35. [PPARα and PPARγ activators suppress the monocyte-macrophage apoB-48 receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
36. [MicroRNA-21 targets peroxisome proliferators-activated receptor-α in an autoregulatory loop to modulate flow-induced endothelial inflammation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
37. [Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR alpha and PPAR gamma-dependent pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
38. [SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
39. [Regulation of LPCAT3 by LXR](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07869&geneProductId=UniProtKB:Q07869)
40. [A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
41. [Regulation of LPCAT3 by LXR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07869)
42. Ensembl Release 99