# peroxiredoxin 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21114645](https://www.wikidata.org/wiki/Q21114645)  
**Source**: https://4ort.xyz/entity/peroxiredoxin-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P30048)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
5. [Silencing of peroxiredoxin 3 and peroxiredoxin 5 reveals the role of mitochondrial peroxiredoxins in the protection of human neuroblastoma SH-SY5Y cells toward MPP+](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
6. [AOP-1 interacts with cardiac-specific protein kinase TNNI3K and down-regulates its kinase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
7. [Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
8. [RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
9. [Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
10. [Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
11. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
12. [Mammalian antioxidant protein complements alkylhydroperoxide reductase (ahpC) mutation in Escherichia coli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
13. [Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
14. [Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
15. [Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
16. [Reconstitution of the mitochondrial PrxIII antioxidant defence pathway: general properties and factors affecting PrxIII activity and oligomeric state](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
17. [Cloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin family](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
18. [Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
19. [Model for the exceptional reactivity of peroxiredoxins 2 and 3 with hydrogen peroxide: a kinetic and computational study](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
20. [Cryo-electron microscopy structure of human peroxiredoxin-3 filament reveals the assembly of a putative chaperone.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
21. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
25. [Silencing of peroxiredoxin 3 and peroxiredoxin 5 reveals the role of mitochondrial peroxiredoxins in the protection of human neuroblastoma SH-SY5Y cells toward MPP+](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
26. [Localization and H2O2-specific induction of PRDX3 in the eye lens](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
27. [Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
28. [AOP-1 interacts with cardiac-specific protein kinase TNNI3K and down-regulates its kinase activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P30048&geneProductId=UniProtKB:P30048)
29. [Localization and H2O2-specific induction of PRDX3 in the eye lens](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
30. [The c-Myc target gene PRDX3 is required for mitochondrial homeostasis and neoplastic transformation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
31. [FOXO3A regulates peroxiredoxin III expression in human cardiac fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30048)
32. Ensembl Release 99
33. UMLS 2023