# Paxillin

> mammalian protein found in Mus musculus

**Wikidata**: [Q14906595](https://www.wikidata.org/wiki/Q14906595)  
**Source**: https://4ort.xyz/entity/paxillin-q14906595


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8VI36)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
5. [Interaction of bcl-2 with Paxillin through its BH4 domain is important during ureteric bud branching](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
6. [EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
7. [LIM kinase 2 is widely expressed in all tissues](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
8. [Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
9. [Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
10. [Transformation Suppression by Protein Tyrosine Phosphatase 1B Requires a Functional SH3 Ligand](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
11. [FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
12. [EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
13. [The Adaptor Protein Paxillin Is Essential for Normal Development in the Mouse and Is a Critical Transducer of Fibronectin Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
14. [Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
16. [Linkage of caspase-mediated degradation of paxillin to apoptosis in Ba/F3 murine pro-B lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
17. [Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
18. [Dysregulation of energy homeostasis in mice overexpressing insulin-like growth factor-binding protein 6 in the brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
19. [The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
20. [Phosphoinositide 3-kinase p85beta regulates invadopodium formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
21. [The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
22. [Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
23. [Mutations in the Paxillin-binding Site of Integrin-linked Kinase (ILK) Destabilize the Pseudokinase Domain and Cause Embryonic Lethality in Mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
24. [Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
25. [Integrin-β5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor β](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36)
26. ensembl Release 106