# Patched 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21135193](https://www.wikidata.org/wiki/Q21135193)  
**Source**: https://4ort.xyz/entity/patched-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13635)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
5. [Characterization of two patched receptors for the vertebrate hedgehog protein family](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13635&geneProductId=UniProtKB:Q13635)
6. [The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membrane](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13635&geneProductId=UniProtKB:Q13635)
7. [The hedgehog receptor patched is involved in cholesterol transport](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
8. [The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
9. [Kinase activity-independent regulation of cyclin pathway by GRK2 is essential for zebrafish early development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
10. [Ligand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13635&geneProductId=UniProtKB:Q13635)
12. [Patched1 interacts with cyclin B1 to regulate cell cycle progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
13. [The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
14. [Characterization of two patched receptors for the vertebrate hedgehog protein family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
16. [Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13635&geneProductId=UniProtKB:Q13635)
17. [Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
18. [Immunohistochemical analysis of Sonic hedgehog signalling in normal human urinary tract development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
19. [Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
20. [The sonic hedgehog-patched-gli pathway in human development and disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
21. [Inhibition of GLI1 gene activation by Patched1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
22. [Immunohistochemical analysis of Sonic hedgehog signalling in normal human urinary tract development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13635&geneProductId=UniProtKB:Q13635)
23. [Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13635)
24. Ensembl Release 99
25. Transporter Classification database