# Partner and localizer of BRCA2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21155274](https://www.wikidata.org/wiki/Q21155274)  
**Source**: https://4ort.xyz/entity/partner-and-localizer-of-brca2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q86YC2)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
5. [Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
6. [MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
7. [PALB2 regulates recombinational repair through chromatin association and oligomerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
8. [PALB2 is an integral component of the BRCA complex required for homologous recombination repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
9. [APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
10. [Structural basis for recruitment of BRCA2 by PALB2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
11. [DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
12. [Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
13. [Structural Basis for Molecular Interactions Involving MRG Domains: Implications in Chromatin Biology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
14. [Compromised BRCA1-PALB2 interaction is associated with breast cancer risk.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
15. [Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
16. [Analysis of PALB2/FANCN-associated breast cancer families](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
17. [A mechanism for the suppression of homologous recombination in G1 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
18. [ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
19. [Structural Basis for Multi-specificity of MRG Domains.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
20. [NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YC2)
21. Ensembl Release 99