negative regulation of neuron apoptotic process
negative regulation of insulin secretion
positive regulation of mitophagy in response to mitochondrial depolarization
positive regulation of mitochondrial fission
SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination
PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease
A Product of the Human Gene Adjacent to parkin Is a Component of Lewy Bodies and Suppresses Pael Receptor-induced Cell Death
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
Loss of laforin or malin results in increased Drp1 level and concomitant mitochondrial fragmentation in Lafora disease mouse models
Parkin interacts with Klokin1 for mitochondrial import and maintenance of membrane potential
14-3-3eta is a novel regulator of parkin ubiquitin ligase
Parkin ubiquitinates and promotes the degradation of RanBP2
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Identification of the Ubiquitin-like Domain of Midnolin as a New Glucokinase Interaction Partner
Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1
Differential expression and tissue distribution of parkin isoforms during mouse development
Parkin occurs in a stable, non-covalent, approximately 110-kDa complex in brain
Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling
Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
Parkin-deficient mice are not a robust model of parkinsonism
Cannabinoid CB(1) receptors in the basal ganglia and motor response to activation or blockade of these receptors in parkin-null mice
Loss of locus coeruleus neurons and reduced startle in parkin null mice
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO
Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation
Memory and exploratory impairment in mice that lack the Park-2 gene and that over-express the human FTDP-17 mutant Tau
Mitochondrial dysfunction and oxidative damage in parkin-deficient mice
Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress
MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin