# Parkin Dmel_CG10523

> protein found in Drosophila melanogaster

**Wikidata**: [Q29819624](https://www.wikidata.org/wiki/Q29819624)  
**Source**: https://4ort.xyz/entity/parkin-dmel-cg10523


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q7KTX7)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
5. [Drosophila melanogaster Parkin ubiquitinates peanut and septin1 as an E3 ubiquitin-protein ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
6. [Drosophila melanogaster Parkin ubiquitinates peanut and septin1 as an E3 ubiquitin-protein ligase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
8. [Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
9. [Diminution of eIF4E activity suppresses parkin mutant phenotypes.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7)
10. [Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7)
12. [PINK1 controls mitochondrial localization of Parkin through direct phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7)
13. [Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
14. [Diminution of eIF4E activity suppresses parkin mutant phenotypes.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
15. [PINK1 controls mitochondrial localization of Parkin through direct phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
16. [The PINK1/Parkin pathway regulates mitochondrial morphology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
17. [Mitochondrial Contagion Induced by Parkin Deficiency in Drosophila Hearts and Its Containment by Suppressing Mitofusin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7)
18. [Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
19. [The parkin Mutant Phenotype in the Fly Is Largely Rescued by Metal-Responsive Transcription Factor (MTF-1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
20. [Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
21. [The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
22. [The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
23. [Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
24. [Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
25. [PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
26. [The Drosophila parkin homologue is required for normal mitochondrial dynamics during spermiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
27. [Optimization of wrMTrck to monitor Drosophila larval locomotor activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
28. [Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7)
29. [MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
30. [Parkin suppresses c-Jun N-terminal kinase-induced cell death via transcriptional regulation in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
31. [Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
32. [Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
33. [Zinc supplement greatly improves the condition of parkin mutant Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
34. [Extended lifespan of Drosophila parkin mutants through sequestration of redox-active metals and enhancement of anti-oxidative pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KTX7&geneProductId=UniProtKB:Q7KTX7)
35. [Mitochondrial Contagion Induced by Parkin Deficiency in Drosophila Hearts and Its Containment by Suppressing Mitofusin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
36. [Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
37. [Extended lifespan of Drosophila parkin mutants through sequestration of redox-active metals and enhancement of anti-oxidative pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
38. [Drosophila PINK1 and parkin loss-of-function mutants display a range of non-motor Parkinson's disease phenotypes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KTX7)
39. ensembl Release 106