# paraoxonase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21120457](https://www.wikidata.org/wiki/Q21120457)  
**Source**: https://4ort.xyz/entity/paraoxonase-1-q21120457


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P27169)
3. Q20641742
4. [Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
5. [Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27169&geneProductId=UniProtKB:P27169)
8. [Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27169&geneProductId=UniProtKB:P27169)
9. [Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27169&geneProductId=UniProtKB:P27169)
10. [Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27169&geneProductId=UniProtKB:P27169)
11. [Human Serum Paraoxonase/Arylesterase’s Retained HydrophobicN-Terminal Leader Sequence Associates With HDLs by Binding Phospholipids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
12. [Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
14. [Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
15. [Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27169&geneProductId=UniProtKB:P27169)
16. [Isolation and characterization of human apolipoprotein M-containing lipoproteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
17. [Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
18. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27169&geneProductId=UniProtKB:P27169)
19. [In‐depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27169&geneProductId=UniProtKB:P27169)
20. [The Human Plasma Proteome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
21. [In‐depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
22. [Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
23. [Purified human serum PON1 does not protect LDL against oxidation in the in vitro assays initiated with copper or AAPH](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27169)
24. [Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27169&geneProductId=UniProtKB:P27169)
25. Ensembl Release 99
26. UMLS 2023
27. Transporter Classification database