# Par-3 family cell polarity regulator

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109325](https://www.wikidata.org/wiki/Q21109325)  
**Source**: https://4ort.xyz/entity/par-3-family-cell-polarity-regulator


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8TEW0)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
5. [The keratin-binding protein Albatross regulates polarization of epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
6. [Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
7. [SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
8. [The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
9. [Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
10. [A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
11. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
12. [Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
13. [A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
14. [The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
15. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
16. [Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
17. [Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
18. [Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKCι in complex with a substrate peptide from Par-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TEW0&geneProductId=UniProtKB:Q8TEW0)
21. [CCM1 regulates vascular-lumen organization by inducing endothelial polarity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
22. [Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
23. [Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEW0)
24. Ensembl Release 99