positive regulation of receptor internalization
Par3/HAL, N-terminal domain, protein family
phosphatidylinositol-4,5-bisphosphate binding
phosphatidylinositol-3,4,5-trisphosphate binding
negative regulation of peptidyl-threonine phosphorylation
regulation of actin filament-based process
Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling
The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1
Par3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migration
FRMD4A regulates epithelial polarity by connecting Arf6 activation with the PAR complex
Loss of partitioning-defective-3/isotype-specific interacting protein (par-3/ASIP) in the elongating spermatid of RA175 (IGSF4A/SynCAM)-deficient mice
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
PAR-3 defines a central subdomain of the cortical actin cap in mouse eggs
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions
Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves
Nectins localize Willin to cell–cell junctions
Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells
Spatial regulation of VEGF receptor endocytosis in angiogenesis
Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation
Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse