# Par-3 family cell polarity regulator

> mammalian protein found in Mus musculus

**Wikidata**: [Q21987386](https://www.wikidata.org/wiki/Q21987386)  
**Source**: https://4ort.xyz/entity/par-3-family-cell-polarity-regulator-q21987386


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q99NH2)
3. Q20641742
4. [Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
5. [The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
6. [Par3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
7. [FRMD4A regulates epithelial polarity by connecting Arf6 activation with the PAR complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
8. [Loss of partitioning-defective-3/isotype-specific interacting protein (par-3/ASIP) in the elongating spermatid of RA175 (IGSF4A/SynCAM)-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
9. [Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99NH2&geneProductId=UniProtKB:Q99NH2)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99NH2&geneProductId=UniProtKB:Q99NH2)
13. [PAR-3 defines a central subdomain of the cortical actin cap in mouse eggs](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99NH2&geneProductId=UniProtKB:Q99NH2)
14. [E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
15. [PAR-3 defines a central subdomain of the cortical actin cap in mouse eggs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
16. [Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
17. [Nectins localize Willin to cell–cell junctions](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99NH2&geneProductId=UniProtKB:Q99NH2)
18. [FRMD4A regulates epithelial polarity by connecting Arf6 activation with the PAR complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99NH2&geneProductId=UniProtKB:Q99NH2)
19. [Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99NH2&geneProductId=UniProtKB:Q99NH2)
20. [Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
21. [Nectins localize Willin to cell–cell junctions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
22. [Spatial regulation of VEGF receptor endocytosis in angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
23. [Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
24. [Par3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migration](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99NH2&geneProductId=UniProtKB:Q99NH2)
25. [Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH2)
26. ensembl Release 106