# Paired like homeodomain 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21108503](https://www.wikidata.org/wiki/Q21108503)  
**Source**: https://4ort.xyz/entity/paired-like-homeodomain-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q99697)
3. Q20641742
4. [Dominant Negative Dimerization of a Mutant Homeodomain Protein in Axenfeld-Rieger Syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
5. [Proteomic and genomic analysis of PITX2 interacting and regulating networks](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
6. [The Molecular Basis of Rieger Syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
9. [The Molecular Basis of Rieger Syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
10. [Protein interactions of the transcription factor Hoxa1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
11. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
12. [Proteomic and genomic analysis of PITX2 interacting and regulating networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
13. [Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld–Rieger syndrome and anterior segment dysgenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
14. [Interaction, Cooperative Promoter Modulation, and Renal Colocalization of GCMa and Pitx2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
15. [Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld–Rieger syndrome and anterior segment dysgenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
16. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
19. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
20. [Pitx2, a β-catenin-regulated transcription factor, regulates the differentiation of outer root sheath cells cultured in vitro](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
21. [Interaction, Cooperative Promoter Modulation, and Renal Colocalization of GCMa and Pitx2](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
22. [Pitx2, a β-catenin-regulated transcription factor, regulates the differentiation of outer root sheath cells cultured in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
23. [A model for the molecular underpinnings of tooth defects in Axenfeld–Rieger syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
24. [Expression of the members of the Ptx family of transcription factors in human pituitary adenomas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
25. [PITX2 gain-of-function induced defects in mouse forelimb development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
26. [Mutation in the RIEG1 Gene in Patients with Iridogoniodysgenesis Syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
27. [Novel Identification of a Four-base-pair Deletion Mutation in PITX2 in a Rieger Syndrome Family](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
28. [Autosomal dominant iris hypoplasia is caused by a mutation in the rieger syndrome (rieg/pitx2) gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
29. [Cell-specific Activation of the Atrial Natriuretic Factor Promoter by PITX2 and MEF2A](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99697&geneProductId=UniProtKB:Q99697)
30. [A model for the molecular underpinnings of tooth defects in Axenfeld–Rieger syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
31. [PITX2 gain-of-function induced defects in mouse forelimb development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
32. [Novel Identification of a Four-base-pair Deletion Mutation in PITX2 in a Rieger Syndrome Family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99697)
33. Ensembl Release 99