# Paired box 8

> mammalian protein found in Mus musculus

**Wikidata**: [Q21988403](https://www.wikidata.org/wiki/Q21988403)  
**Source**: https://4ort.xyz/entity/paired-box-8-q21988403


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q00288)
3. Q20641742
4. [PAX8-mediated activation of the wt1 tumor suppressor gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
6. [Pax genes and their role in organogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
7. [The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00288&geneProductId=UniProtKB:Q00288)
9. [TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
10. [Nephric lineage specification by Pax2 and Pax8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
11. [Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
12. [Follicular cells of the thyroid gland require Pax8 gene function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
13. [Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
14. [Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
15. [Regulation of iodothyronine deiodinases in the Pax8-/- mouse model of congenital hypothyroidism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
16. [Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
17. [Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
18. [Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
19. [Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
20. [TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
21. [Expression of microRNA‐122 contributes to apoptosis in H9C2 myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00288)
22. ensembl Release 106