# P21 (RAC1) activated kinase 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109710](https://www.wikidata.org/wiki/Q21109710)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/PAK3)  
**Source**: https://4ort.xyz/entity/p21-rac1-activated-kinase-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O75914)
3. Q20641742
4. [Swiss-Prot](http://www.uniprot.org/uniprot/Q61036.txt?version=157)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75914)
6. [Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75914)
7. [Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75914)
8. [Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75914)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75914&geneProductId=UniProtKB:O75914)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75914&geneProductId=UniProtKB:O75914)
11. [Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75914&geneProductId=UniProtKB:O75914)
12. [The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75914&geneProductId=UniProtKB:O75914)
13. [VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75914&geneProductId=UniProtKB:O75914)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75914)
15. [PAK signalling in neuronal physiology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75914)
16. Ensembl Release 99