# P21 (RAC1) activated kinase 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28556344](https://www.wikidata.org/wiki/Q28556344)  
**Source**: https://4ort.xyz/entity/p21-rac1-activated-kinase-1-q28556344


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P35465)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
5. [Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
6. [Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
7. [Synapsin I is phosphorylated at Ser603 by p21-activated kinases (PAKs) in vitro and in PC12 cells stimulated with bradykinin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
9. [Expression of mitogen-activated protein kinase pathways during postnatal development of rat heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
10. [Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
11. [Phosphorylation and reorganization of vimentin by p21-activated kinase (PAK)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
12. [Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
13. [Dissecting activation of the PAK1 kinase at protrusions in living cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
14. [Intracellular localization and functional effects of P21-activated kinase-1 (Pak1) in cardiac myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
15. [Localized activation of p21-activated kinase controls neuronal polarity and morphology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
16. [Hypoxia and Hypoxia/Reoxygenation Activate p65PAK, p38Mitogen-Activated Protein Kinase (MAPK), and Stress-Activated Protein Kinase (SAPK) in Cultured Rat Cardiac Myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35465&geneProductId=UniProtKB:P35465)
18. [A brain serine/threonine protein kinase activated by Cdc42 and Rac1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
19. [Lysophosphatidic acid stimulates p21-activated kinase in vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
20. [Scaffolding function of PAK in the PDK1-Akt pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
21. [A FOXO-Pak1 transcriptional pathway controls neuronal polarity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
22. [Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
23. [p21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
24. [Conversion of a signal into forces for axon outgrowth through Pak1-mediated shootin1 phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
25. [Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
26. [Membrane targeting of p21-activated kinase 1(PAK1) induces neurite outgrowth from PC12 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
27. [Pak1 as a Novel Therapeutic Target for Antihypertrophic Treatment in the Heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
28. [p21-activated kinase 1 participates in vascular remodeling in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35465)
29. ensembl Release 104