# Opioid related nociceptin receptor 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28559665](https://www.wikidata.org/wiki/Q28559665)  
**Source**: https://4ort.xyz/entity/opioid-related-nociceptin-receptor-1-q28559665


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P35370)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
6. [Heterodimerization of opioid receptor-like 1 and mu-opioid receptors impairs the potency of micro receptor agonist](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
7. [Nociceptin inhibits uterine contractions in term-pregnant rats by signaling through multiple pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
8. [Sex-related differences in the distribution of opioid receptor-like 1 receptor mRNA and colocalization with estrogen receptor mRNA in neurons of the spinal trigeminal nucleus caudalis in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
9. [Opioid receptor-like 1 stimulation in the collecting duct induces aquaresis through vasopressin-independent aquaporin-2 downregulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
10. [Dynorphin A(1-17)-induced feeding: pharmacological characterization using selective opioid antagonists and antisense probes in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
11. [Two C-terminal amino acids, Ser(334) and Ser(335), are required for homologous desensitization and agonist-induced phosphorylation of opioid receptor-like 1 receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
12. [Nociceptin inhibits the neurogenic vasopressor response in the pithed rat via prejunctional ORL1 receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
13. [Buprenorphine activates mu and opioid receptor like-1 receptors simultaneously, but the analgesic effect is mainly mediated by mu receptor activation in the rat formalin test](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
14. [Gastric acid secretion stimulated by centrally injected nociceptin in urethane-anesthetized rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
15. [Modulation of Ca2+ channels by opioid receptor-like 1 receptors natively expressed in rat stellate ganglion neurons innervating cardiac muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
16. [Activation of opioid receptor like-1 receptor in the spinal cord produces sex-specific antinociception in the rat: estrogen attenuates antinociception in the female, whereas testosterone is required for the expression of antinociception in the male](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
17. [Role of nociceptin and opioid receptor like 1 on entrainment function in the rat suprachiasmatic nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
18. [Pharmacological blockade or genetic knockout of the NOP receptor potentiates the rewarding effect of morphine in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35370)
19. ensembl Release 106