# Opioid receptor, kappa 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28562980](https://www.wikidata.org/wiki/Q28562980)  
**Source**: https://4ort.xyz/entity/opioid-receptor-kappa-1-q28562980


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P34975)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
6. [Formation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
7. [G protein coupled receptor kinase-2 upregulation causes κ-opioid receptor desensitization in diabetic heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
8. [Kappa opioid receptors in the rostral ventromedial medulla of male and female rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
9. [Major coexpression of κ‐opioid receptors and the dopamine transporter in nucleus accumbens axonal profiles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
10. [Differential coupling of mu-, delta-, and kappa-opioid receptors to G alpha16-mediated stimulation of phospholipase C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
11. [Electrical and manual acupuncture stimulation affect oestrous cyclicity and neuroendocrine function in an 5α-dihydrotestosterone-induced rat polycystic ovary syndrome model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
12. [Regulation of kappa-opioid receptor mRNA level by cyclic AMP and growth factors in cultured rat glial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
13. [Tyrosine phosphorylation of the kappa -opioid receptor regulates agonist efficacy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
14. [Increased locomotor response to amphetamine induced by the repeated administration of the selective kappa-opioid receptor agonist U-69593](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
15. [dynorphin-kappa opioid receptor signaling partly mediates estrogen negative feedback effect on LH pulses in female rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
16. [Downregulation of kappa opioid receptor mRNA levels by chronic ethanol and repetitive cocaine in rat ventral tegmentum and nucleus accumbens](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
17. [Behavioral meaningful opioidergic stimulation activates kappa receptor gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
18. [Dynorphin A(1-17)-induced feeding: pharmacological characterization using selective opioid antagonists and antisense probes in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
19. [Preliminary study of the effects of morphine treatment on opioid receptor gene expression in brain structures of the female rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
20. [Alterations in kappa opioid receptor mRNA levels in the paraventricular nucleus of the hypothalamus by stress and sex steroids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
21. [Repeated stress exposure causes strain-dependent shifts in the behavioral economics of cocaine in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
22. [kappa -opioid receptor agonists modulate visceral nociception at a novel, peripheral site of action](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
23. [Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
24. [Phosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
25. [Neurobehavioral and transcriptional effects of acrylamide in juvenile rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
26. [The effect of kappa opioid receptor antagonism on energy expenditure in the obese Zucker rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
27. [Inhibitory effects of processed Aconiti tuber on morphine-induced conditioned place preference in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34975)
28. ensembl Release 106