# OCRL inositol polyphosphate-5-phosphatase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7072378](https://www.wikidata.org/wiki/Q7072378)  
**Source**: https://4ort.xyz/entity/ocrl-inositol-polyphosphate-5-phosphatase-q7072378


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q01968)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01968&geneProductId=UniProtKB:Q01968)
5. [The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01968&geneProductId=UniProtKB:Q01968)
6. [The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
7. [OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
8. [Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
9. [Lowe syndrome protein OCRL1 interacts with Rac GTPase in the trans-Golgi network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
10. [Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
11. [A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
12. [A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
13. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
14. [A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
15. [Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
17. [Lowe syndrome protein OCRL1 interacts with Rac GTPase in the trans-Golgi network](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01968&geneProductId=UniProtKB:Q01968)
18. [The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
19. [The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01968&geneProductId=UniProtKB:Q01968)
22. [The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01968&geneProductId=UniProtKB:Q01968)
23. [Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01968&geneProductId=UniProtKB:Q01968)
24. [β-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the golgi complex, shows homology to β-adaptin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
25. [OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01968&geneProductId=UniProtKB:Q01968)
26. [The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01968&geneProductId=UniProtKB:Q01968)
27. [The Lowe syndrome protein OCRL1 is involved in primary cilia assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01968)
28. Ensembl Release 99