NUS1 dehydrodolichyl diphosphate synthase subunit
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Decaprenyl diphosphate synthase-like superfamily
additional property: PropertyValue
  property ID: P361
  value: Decaprenyl diphosphate synthase-like
additional property: PropertyValue
  property ID: P361
  value: Dehydrodolichyl diphosphate synthase complex subunit Nus1
additional property: PropertyValue
  property ID: P637
  value: NP_612468
additional property: PropertyValue
  property ID: P680
  value: transferase activity
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P680
  value: prenyltransferase activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: endoplasmic reticulum membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: cell differentiation
additional property: PropertyValue
  property ID: P682
  value: dolichol biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: regulation of intracellular cholesterol transport
additional property: PropertyValue
  property ID: P702
  value: NUS1
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000357480
additional property: PropertyValue
  property ID: P2888
  value: http://purl.uniprot.org/uniprot/Q96E22
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 14
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 14
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q96E22
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797537
    source count: 1
    confidence: 0.2
    value label: Decaprenyl diphosphate synthase-like superfamily
  P361:
    value: Q24771083
    source count: 1
    confidence: 0.2
    value label: Decaprenyl diphosphate synthase-like
  P361:
    value: Q54461933
    source count: 1
    confidence: 0.2
    value label: Dehydrodolichyl diphosphate synthase complex subunit Nus1
  P637:
    value: NP_612468
    source count: 1
    confidence: 0.2
  P680:
    value: Q14840131
    source count: 1
    confidence: 0.2
    value label: transferase activity
  P680:
    value: Q167149
    source count: 1
    confidence: 0.2
    value label: protein binding
  P680:
    value: Q21110678
    source count: 2
    confidence: 0.4
    value label: prenyltransferase activity
  P680:
    value: Q21117494
    source count: 1
    confidence: 0.2
    value label: transferase activity, transferring alkyl or aryl (other than methyl) groups
  P680:
    value: Q14860489
    source count: 1
    confidence: 0.2
    value label: molecular function
  P681:
    value: Q14327652
    source count: 1
    confidence: 0.2
    value label: integral component of membrane
  P681:
    value: Q14329032
    source count: 3
    confidence: 0.6
    value label: endoplasmic reticulum membrane
  P681:
    value: Q14349455
    source count: 2
    confidence: 0.4
    value label: membrane
  P681:
    value: Q79927
    source count: 1
    confidence: 0.2
    value label: endoplasmic reticulum
  P681:
    value: Q22326923
    source count: 1
    confidence: 0.2
    value label: dehydrodolichyl diphosphate synthase complex
  P682:
    value: Q210861
    source count: 1
    confidence: 0.2
    value label: cell differentiation
  P682:
    value: Q21110679
    source count: 1
    confidence: 0.2
    value label: dolichol biosynthetic process
  P682:
    value: Q21110681
    source count: 2
    confidence: 0.4
    value label: regulation of intracellular cholesterol transport
  P682:
    value: Q21112286
    source count: 1
    confidence: 0.2
    value label: sterol homeostasis
  P682:
    value: Q14645705
    source count: 1
    confidence: 0.2
    value label: multicellular organism development
  P702:
    value: Q18049203
    source count: 1
    confidence: 0.2
    value label: NUS1
  P703:
    value: Q15978631
    source count: 1
    confidence: 0.2
    value label: Homo sapiens
  P705:
    value: ENSP00000357480
    source count: 1
    confidence: 0.2
  P2888:
    value: http://purl.uniprot.org/uniprot/Q96E22
    source count: 1
    confidence: 0.2
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-04-08
citations:
  source: Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation
  stated in qid: Q24302402
  retrieved: 2019-04-08

source: Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation
stated in qid: Q24301443
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-07-16

source: A conserved C-terminal RXG motif in the NgBR subunit of cis-prenyltransferase is critical for prenyltransferase activity.
stated in qid: Q47904068
retrieved: 2019-04-08

source: Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking
stated in qid: Q24311592
retrieved: 2019-04-08

source: Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation
stated in qid: Q24301443
retrieved: 2018-04-24

source: Endothelial miR-26a regulates VEGF-Nogo-B receptor-mediated angiogenesis.
stated in qid: Q41616135
retrieved: 2019-04-08

source: A conserved C-terminal RXG motif in the NgBR subunit of cis-prenyltransferase is critical for prenyltransferase activity.
stated in qid: Q47904068
retrieved: 2018-09-10

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

source: Identifiers.org
stated in qid: Q16335166

wikidata id: Q21110682
domain: protein
level: standard
html url: https://4ort.xyz/entity/nus1-dehydrodolichyl-diphosphate-synthase-subunit-q21110682
markdown url: https://4ort.xyz/entity/nus1-dehydrodolichyl-diphosphate-synthase-subunit-q21110682.md
facts url summary: https://4ort.xyz/entity/nus1-dehydrodolichyl-diphosphate-synthase-subunit-q21110682/facts.json
facts url standard: https://4ort.xyz/entity/nus1-dehydrodolichyl-diphosphate-synthase-subunit-q21110682/facts.json
facts url full: https://4ort.xyz/entity/nus1-dehydrodolichyl-diphosphate-synthase-subunit-q21110682/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-02T05:31:22.300711Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:25:56.647217+00:00Z