# Nudix hydrolase 21

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21132119](https://www.wikidata.org/wiki/Q21132119)  
**Source**: https://4ort.xyz/entity/nudix-hydrolase-21


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O43809)
3. Q20641742
4. [Crystal structure of a human cleavage factor CFI(m)25/CFI(m)68/RNA complex provides an insight into poly(A) site recognition and RNA looping](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
5. [Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
6. [Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
7. [VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
8. [Association of polyadenylation cleavage factor I with U1 snRNP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
9. [Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
10. [Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
11. [Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
12. [Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
13. [Interaction of Poly(A) Polymerase with the 25-kDa Subunit of Cleavage Factor I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
14. [Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
15. [A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
16. [Alternative 3'-end processing of long noncoding RNA initiates construction of nuclear paraspeckles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
17. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
18. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
19. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
20. [A Y2H-seq approach defines the human protein methyltransferase interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
21. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43809&geneProductId=UniProtKB:O43809)
22. [Crystal structure of a human cleavage factor CFI(m)25/CFI(m)68/RNA complex provides an insight into poly(A) site recognition and RNA looping](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43809&geneProductId=UniProtKB:O43809)
23. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
24. [Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43809&geneProductId=UniProtKB:O43809)
25. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43809&geneProductId=UniProtKB:O43809)
26. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43809&geneProductId=UniProtKB:O43809)
27. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43809&geneProductId=UniProtKB:O43809)
28. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43809&geneProductId=UniProtKB:O43809)
29. [Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43809&geneProductId=UniProtKB:O43809)
30. [Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
31. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
32. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
33. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
34. [Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43809&geneProductId=UniProtKB:O43809)
35. [Cleavage factor Im is a key regulator of 3' UTR length](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
36. [Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3'-UTRs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43809)
37. Ensembl Release 99