Nuclear receptor subfamily 5 group A member 2
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: O00482
additional property: PropertyValue
  property ID: P361
  value: Nuclear hormone receptor-like domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Zinc finger, NHR/GATA-type
additional property: PropertyValue
  property ID: P361
  value: Nuclear hormone receptor family 5
additional property: PropertyValue
  property ID: P527
  value: nuclear hormone receptor-type zinc finger
additional property: PropertyValue
  property ID: P527
  value: Nuclear hormone receptor, ligand-binding domain
additional property: PropertyValue
  property ID: P637
  value: NP_001263393
additional property: PropertyValue
  property ID: P637
  value: NP_003813
additional property: PropertyValue
  property ID: P637
  value: NP_995582
additional property: PropertyValue
  property ID: P638
  value: 4RWV
additional property: PropertyValue
  property ID: P638
  value: 1YOK
additional property: PropertyValue
  property ID: P638
  value: 1YUC
additional property: PropertyValue
  property ID: P680
  value: RNA polymerase II cis-regulatory region sequence-specific DNA binding
additional property: PropertyValue
  property ID: P680
  value: DNA binding
additional property: PropertyValue
  property ID: P680
  value: sequence-specific DNA binding
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: nucleoplasm
additional property: PropertyValue
  property ID: P681
  value: RNA polymerase II transcription regulator complex
additional property: PropertyValue
  property ID: P682
  value: regulation of transcription, DNA-templated
additional property: PropertyValue
  property ID: P682
  value: epithelial cell differentiation
additional property: PropertyValue
  property ID: P682
  value: pancreas morphogenesis
additional property: PropertyValue
  property ID: P702
  value: NR5A2
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000439116
additional property: PropertyValue
  property ID: P705
  value: ENSP00000236914
additional property: PropertyValue
  property ID: P705
  value: ENSP00000356331
additional property: PropertyValue
  property ID: P7260
  value: 9.B.208.1.4
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 24
      unique citations norm: 0.009
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 24
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: O00482
    source count: 1
    confidence: 0.2
  P361:
    value: Q41796865
    source count: 1
    confidence: 0.2
    value label: Nuclear hormone receptor-like domain superfamily
  P361:
    value: Q24768526
    source count: 1
    confidence: 0.2
    value label: Zinc finger, NHR/GATA-type
  P361:
    value: Q24785591
    source count: 1
    confidence: 0.2
    value label: Nuclear hormone receptor family 5
  P361:
    value: Q83140722
    source count: 1
    confidence: 0.2
    value label: Nuclear hormone receptor, ligand-binding domain, protein family
  P361:
    value: Q83135095
    source count: 1
    confidence: 0.2
    value label: Zinc finger, nuclear hormone receptor-type, protein family
  P527:
    value: Q24725588
    source count: 1
    confidence: 0.2
    value label: nuclear hormone receptor-type zinc finger
  P527:
    value: Q24772746
    source count: 1
    confidence: 0.2
    value label: Nuclear hormone receptor, ligand-binding domain
  P637:
    value: NP_001263393
    source count: 1
    confidence: 0.2
  P637:
    value: NP_003813
    source count: 1
    confidence: 0.2
  P637:
    value: NP_995582
    source count: 1
    confidence: 0.2
  P637:
    value: XP_005245119
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011507682
    source count: 1
    confidence: 0.2
  P638:
    value: 4RWV
    source count: 1
    confidence: 0.2
  P638:
    value: 1YOK
    source count: 1
    confidence: 0.2
  P638:
    value: 1YUC
    source count: 1
    confidence: 0.2
  P638:
    value: 1ZDU
    source count: 1
    confidence: 0.2
  P638:
    value: 2A66
    source count: 1
    confidence: 0.2
  P680:
    value: Q14885806
    source count: 2
    confidence: 0.4
    value label: RNA polymerase II cis-regulatory region sequence-specific DNA binding
  P680:
    value: Q14633858
    source count: 4
    confidence: 0.8
    value label: DNA binding
  P680:
    value: Q14818107
    source count: 2
    confidence: 0.4
    value label: sequence-specific DNA binding

value: Q14817979
source count: 4
confidence: 0.8
value label: DNA-binding transcription factor activity

value: Q14633865
source count: 1
confidence: 0.2
value label: zinc ion binding

value: Q79899
source count: 1
confidence: 0.2
value label: cytoplasm

value: Q14817956
source count: 1
confidence: 0.2
value label: nucleoplasm

value: Q21095257
source count: 3
confidence: 0.6
value label: RNA polymerase II transcription regulator complex

value: Q40260
source count: 5
confidence: 1.0
value label: nucleus

value: Q14633883
source count: 3
confidence: 0.6
value label: regulation of transcription, DNA-templated

value: Q14863097
source count: 1
confidence: 0.2
value label: epithelial cell differentiation

value: Q14897670
source count: 1
confidence: 0.2
value label: pancreas morphogenesis

value: Q14851908
source count: 1
confidence: 0.2
value label: bile acid metabolic process

value: Q14763010
source count: 1
confidence: 0.2
value label: transcription, DNA-templated

value: Q15312697
source count: 1
confidence: 0.2
value label: NR5A2

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000439116
source count: 1
confidence: 0.2

value: ENSP00000236914
source count: 1
confidence: 0.2

value: ENSP00000356331
source count: 1
confidence: 0.2

value: ENSP00000356326
source count: 1
confidence: 0.2

value: ENSP00000414888
source count: 1
confidence: 0.2

value: 9.B.208.1.4
source count: 2
confidence: 0.4

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity
stated in qid: Q24295077
retrieved: 2019-04-08

source: Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP
stated in qid: Q24295257
retrieved: 2019-04-08

source: Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene
stated in qid: Q24297189
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-09-10

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: An intronic peroxisome proliferator-activated receptor-binding sequence mediates fatty acid induction of the human carnitine palmitoyltransferase 1A
stated in qid: Q24293662
retrieved: 2018-04-24

source: Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism
stated in qid: Q24298601
retrieved: 2019-04-08

source: Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17
stated in qid: Q24323350
retrieved: 2019-04-08

source: Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit
stated in qid: Q24303852
retrieved: 2019-04-08

source: Functional conservation of interactions between a homeodomain cofactor and a mammalian FTZ-F1 homologue
stated in qid: Q24293122
retrieved: 2019-04-08

source: Prospero-related homeobox protein (Prox1) inhibits hepatitis B virus replication through repressing multiple cis regulatory elements
stated in qid: Q24317749
retrieved: 2019-04-08

source: Cloning and characterization of a novel human hepatocyte transcription factor, hB1F, which binds and activates enhancer II of hepatitis B virus
stated in qid: Q22004000
retrieved: 2018-09-10

source: A census of human transcription factors: function, expression and evolution
stated in qid: Q29622841
retrieved: 2018-09-10

source: An intronic peroxisome proliferator-activated receptor-binding sequence mediates fatty acid induction of the human carnitine palmitoyltransferase 1A
stated in qid: Q24293662
retrieved: 2019-04-08

source: Cloning and characterization of a novel human hepatocyte transcription factor, hB1F, which binds and activates enhancer II of hepatitis B virus
stated in qid: Q22004000
retrieved: 2019-04-08

source: A census of human transcription factors: function, expression and evolution
stated in qid: Q29622841
retrieved: 2019-04-08

source: Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene
stated in qid: Q24297189
retrieved: 2018-11-07

source: Functional conservation of interactions between a homeodomain cofactor and a mammalian FTZ-F1 homologue
stated in qid: Q24293122
retrieved: 2018-11-07

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q6658210
domain: protein
level: standard
html url: https://4ort.xyz/entity/nuclear-receptor-subfamily-5-group-a-member-2-q6658210
markdown url: https://4ort.xyz/entity/nuclear-receptor-subfamily-5-group-a-member-2-q6658210.md
facts url summary: https://4ort.xyz/entity/nuclear-receptor-subfamily-5-group-a-member-2-q6658210/facts.json
facts url standard: https://4ort.xyz/entity/nuclear-receptor-subfamily-5-group-a-member-2-q6658210/facts.json
facts url full: https://4ort.xyz/entity/nuclear-receptor-subfamily-5-group-a-member-2-q6658210/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-02T22:56:57.849454Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:22:28.940318+00:00Z