Nuclear receptor subfamily 5, group A, member 1
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P33242
additional property: PropertyValue
  property ID: P361
  value: Nuclear hormone receptor-like domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Zinc finger, NHR/GATA-type
additional property: PropertyValue
  property ID: P361
  value: Nuclear hormone receptor family 5
additional property: PropertyValue
  property ID: P527
  value: Nuclear hormone receptor, ligand-binding domain
additional property: PropertyValue
  property ID: P527
  value: nuclear hormone receptor-type zinc finger
additional property: PropertyValue
  property ID: P637
  value: NP_001303616
additional property: PropertyValue
  property ID: P637
  value: NP_620639
additional property: PropertyValue
  property ID: P638
  value: 1YMT
additional property: PropertyValue
  property ID: P638
  value: 1YP0
additional property: PropertyValue
  property ID: P638
  value: 2FF0
additional property: PropertyValue
  property ID: P680
  value: RNA polymerase II cis-regulatory region sequence-specific DNA binding
additional property: PropertyValue
  property ID: P680
  value: DNA binding
additional property: PropertyValue
  property ID: P680
  value: zinc ion binding
additional property: PropertyValue
  property ID: P681
  value: RNA polymerase II transcription regulator complex
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P681
  value: RNA polymerase II transcription regulator complex
additional property: PropertyValue
  property ID: P682
  value: cell differentiation
additional property: PropertyValue
  property ID: P682
  value: luteinization
additional property: PropertyValue
  property ID: P682
  value: regulation of transcription, DNA-templated
additional property: PropertyValue
  property ID: P702
  value: Nr5a1
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000028084
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000108504
confidence:
  popularity graph score:
    score: 0.005
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 33
      unique citations norm: 0.013
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 33
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P33242
    source count: 1
    confidence: 0.2
  P361:
    value: Q41796865
    source count: 1
    confidence: 0.2
    value label: Nuclear hormone receptor-like domain superfamily
  P361:
    value: Q24768526
    source count: 1
    confidence: 0.2
    value label: Zinc finger, NHR/GATA-type
  P361:
    value: Q24785591
    source count: 1
    confidence: 0.2
    value label: Nuclear hormone receptor family 5
  P361:
    value: Q83140722
    source count: 1
    confidence: 0.2
    value label: Nuclear hormone receptor, ligand-binding domain, protein family
  P361:
    value: Q83135095
    source count: 1
    confidence: 0.2
    value label: Zinc finger, nuclear hormone receptor-type, protein family
  P527:
    value: Q24772746
    source count: 1
    confidence: 0.2
    value label: Nuclear hormone receptor, ligand-binding domain
  P527:
    value: Q24725588
    source count: 1
    confidence: 0.2
    value label: nuclear hormone receptor-type zinc finger
  P637:
    value: NP_001303616
    source count: 1
    confidence: 0.2
  P637:
    value: NP_620639
    source count: 1
    confidence: 0.2
  P638:
    value: 1YMT
    source count: 1
    confidence: 0.2
  P638:
    value: 1YP0
    source count: 1
    confidence: 0.2
  P638:
    value: 2FF0
    source count: 1
    confidence: 0.2
  P638:
    value: 3F7D
    source count: 1
    confidence: 0.2
  P680:
    value: Q14885806
    source count: 1
    confidence: 0.2
    value label: RNA polymerase II cis-regulatory region sequence-specific DNA binding
  P680:
    value: Q14633858
    source count: 7
    confidence: 1.0
    value label: DNA binding
  P680:
    value: Q14633865
    source count: 1
    confidence: 0.2
    value label: zinc ion binding
  P680:
    value: Q14817976
    source count: 2
    confidence: 0.4
    value label: chromatin binding
  P680:
    value: Q13667380
    source count: 1
    confidence: 0.2
    value label: metal ion binding
  P681:
    value: Q21095257
    source count: 1
    confidence: 0.2
    value label: RNA polymerase II transcription regulator complex

value: Q40260
source count: 5
confidence: 1.0
value label: nucleus

value: Q21095257
source count: 2
confidence: 0.4
value label: RNA polymerase II transcription regulator complex

value: Q210861
source count: 1
confidence: 0.2
value label: cell differentiation

value: Q15312522
source count: 1
confidence: 0.2
value label: luteinization

value: Q14633883
source count: 2
confidence: 0.4
value label: regulation of transcription, DNA-templated

value: Q14852032
source count: 1
confidence: 0.2
value label: regulation of transcription by RNA polymerase II

value: Q14819869
source count: 4
confidence: 0.8
value label: adrenal gland development

value: Q15312543
source count: 1
confidence: 0.2
value label: Nr5a1

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000028084
source count: 1
confidence: 0.2

value: ENSMUSP00000108504
source count: 1
confidence: 0.2

source: Transcriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54 nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1)
stated in qid: Q28510034
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse Follicle-stimulating hormone-beta gene
stated in qid: Q28591693
retrieved: 2019-02-14

source: The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development
stated in qid: Q28506797
retrieved: 2019-02-14

source: Differential requirement for steroidogenic factor-1 gene dosage in adrenal development versus endocrine function
stated in qid: Q28513980
retrieved: 2019-02-14

source: Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation
stated in qid: Q28594208
retrieved: 2018-07-16

source: Transcriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54 nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1)
stated in qid: Q28510034
retrieved: 2018-07-16

source: Tpit determines alternate fates during pituitary cell differentiation
stated in qid: Q28508185
retrieved: 2019-02-14

source: SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro
stated in qid: Q28589100
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-09-10

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation
stated in qid: Q28594208
retrieved: 2019-02-14

source: Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA
stated in qid: Q22254231
retrieved: 2019-02-14

source: Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development
stated in qid: Q28510433
retrieved: 2019-02-14

source: Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function
stated in qid: Q28590881
retrieved: 2019-02-14

source: T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors
stated in qid: Q24681142
retrieved: 2019-02-14

source: Interaction between Dax-1 and steroidogenic factor-1 in vivo: increased adrenal responsiveness to ACTH in the absence of Dax-1
stated in qid: Q28594777
retrieved: 2019-02-14

source: Lack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cells
stated in qid: Q28589760
retrieved: 2019-02-14

source: Eliminating SF-1 (NR5A1) Sumoylation In Vivo Results in Ectopic Hedgehog Signaling and Disruption of Endocrine Development
stated in qid: Q28513287
retrieved: 2019-02-14

source: Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern
stated in qid: Q28590895
retrieved: 2019-02-14

source: Lack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cells
stated in qid: Q28589760
retrieved: 2018-07-16

source: Role of the LXXLL-motif and activation function 2 domain in subcellular localization of Dax-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1)
stated in qid: Q28505648
retrieved: 2019-02-14

source: Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice
stated in qid: Q28593808
retrieved: 2018-07-16

source: SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro
stated in qid: Q28589100
retrieved: 2018-07-16

source: Dax-1 as one of the target genes of Ad4BP/SF-1
stated in qid: Q28512958
retrieved: 2018-07-16

source: The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development
stated in qid: Q28506797
retrieved: 2018-07-16

source: The transcription co-factor CITED2 functions during sex determination and early gonad development
stated in qid: Q28594232
retrieved: 2019-02-14

source: Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice
stated in qid: Q28593808
retrieved: 2019-02-14

source: Dax-1 as one of the target genes of Ad4BP/SF-1
stated in qid: Q28512958
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

wikidata id: Q15312559
domain: protein
level: standard
html url: https://4ort.xyz/entity/nuclear-receptor-subfamily-5-group-a-member-1-q15312559
markdown url: https://4ort.xyz/entity/nuclear-receptor-subfamily-5-group-a-member-1-q15312559.md
facts url summary: https://4ort.xyz/entity/nuclear-receptor-subfamily-5-group-a-member-1-q15312559/facts.json
facts url standard: https://4ort.xyz/entity/nuclear-receptor-subfamily-5-group-a-member-1-q15312559/facts.json
facts url full: https://4ort.xyz/entity/nuclear-receptor-subfamily-5-group-a-member-1-q15312559/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-04T09:34:12.113641Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:24:30.033700+00:00Z