# nuclear receptor subfamily 1 group I member 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q409867](https://www.wikidata.org/wiki/Q409867)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Pregnane_X_receptor)  
**Source**: https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-i-member-2


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O75469)
4. Q20641742
5. Freebase Data Dumps. 2013
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
7. [Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75469&geneProductId=UniProtKB:O75469)
8. [Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
9. [The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
10. [2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
11. [Human ADA3 regulates RARalpha transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
12. [Structural and Functional Analysis of the Human Nuclear Xenobiotic Receptor PXR in Complex with RXRα](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
13. [Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
14. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75469&geneProductId=UniProtKB:O75469)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O75469&geneProductId=UniProtKB:O75469)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
17. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
18. [SXR, a novel steroid and xenobiotic-sensing nuclear receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
19. [Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75469)
20. Ensembl Release 99
21. Identifiers.org
22. UMLS 2023
23. Transporter Classification database
24. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)