# nuclear receptor corepressor 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q22683558](https://www.wikidata.org/wiki/Q22683558)  
**Source**: https://4ort.xyz/entity/nuclear-receptor-corepressor-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9Y618)
3. Q20641742
4. [Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y618&geneProductId=UniProtKB:Q9Y618)
5. [The functional relationship between co-repressor N-CoR and SMRT in mediating transcriptional repression by thyroid hormone receptor alpha](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y618&geneProductId=UniProtKB:Q9Y618)
6. [TBLR1 regulates the expression of nuclear hormone receptor co-repressors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
7. [A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y618&geneProductId=UniProtKB:Q9Y618)
8. [Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y618&geneProductId=UniProtKB:Q9Y618)
9. [SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y618&geneProductId=UniProtKB:Q9Y618)
12. [The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
13. [Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
14. [FBI-1 functions as a novel AR co-repressor in prostate cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
15. [A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
16. [Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
17. [A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
18. [Enhancer activation requires trans-recruitment of a mega transcription factor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
19. [Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
20. [Activation of p53 Transcriptional Activity by SMRT: a Histone Deacetylase 3-Independent Function of a Transcriptional Corepressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
21. [The histone demethylase PHF8 governs retinoic acid response in acute promyelocytic leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
22. [Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
23. [A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
24. [The functional interactome landscape of the human histone deacetylase family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
25. [A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
26. [A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
27. [Isolation and Characterization of a Novel Class II Histone Deacetylase, HDAC10](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
28. [Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
29. [Structural insights into the recruitment of SMRT by the corepressor SHARP under phosphorylative regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
30. [Structure of HDAC3 bound to co-repressor and inositol tetraphosphate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
31. [A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
32. [Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
33. [Ataxin‐1 and Brother of ataxin‐1 are components of the Notch signalling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
34. [Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
35. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
36. [Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
37. [The functional relationship between co-repressor N-CoR and SMRT in mediating transcriptional repression by thyroid hormone receptor alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
38. [Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
39. [Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
40. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y618&geneProductId=UniProtKB:Q9Y618)
41. [ZNF703 gene amplification at 8p12 specifies luminal B breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
42. [SMRTe, a silencing mediator for retinoid and thyroid hormone receptors-extended isoform that is more related to the nuclear receptor corepressor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y618&geneProductId=UniProtKB:Q9Y618)
43. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
44. [MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
45. [SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y618&geneProductId=UniProtKB:Q9Y618)
46. [MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y618&geneProductId=UniProtKB:Q9Y618)
47. [SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y618)
48. Ensembl Release 99
49. UMLS 2023