# Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

> mammalian protein found in Mus musculus

**Wikidata**: [Q15325126](https://www.wikidata.org/wiki/Q15325126)  
**Source**: https://4ort.xyz/entity/nuclear-factor-of-kappa-light-polypeptide-gene-enhancer-in-b-cells-inhibitor-alpha


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9Z1E3)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
5. [Mouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaB](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
6. [Direct involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IκBα](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
7. [The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
8. [Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13).](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
9. [Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
10. [Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
11. [A fourth IkappaB protein within the NF-kappaB signaling module](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
12. [Regulation of nuclear translocation of HDAC3 by IkappaBalpha is required for tumor necrosis factor inhibition of peroxisome proliferator-activated receptor gamma function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
13. [NF-kappaB dictates the degradation pathway of IkappaBalpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
14. [Bioinformatics and cellular signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
15. [Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
16. [IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1E3&geneProductId=UniProtKB:Q9Z1E3)
18. [The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
19. [JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
20. [Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
21. [The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
22. [Identification of Lps2 as a key transducer of MyD88-independent TIR signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
23. [JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1E3&geneProductId=UniProtKB:Q9Z1E3)
24. [Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
25. [Angiopoietin-1 mediates the proangiogenic activity of the bone morphogenic protein antagonist Drm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
26. [Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
27. [Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
28. [MicroRNA-494, Upregulated by Tumor Necrosis Factor-α, Desensitizes Insulin Effect in C2C12 Muscle Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1E3)
29. ensembl Release 106