Nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P361
  value: p53-like transcription factor, DNA-binding
additional property: PropertyValue
  property ID: P361
  value: Immunoglobulin-like fold
additional property: PropertyValue
  property ID: P361
  value: Rel homology domain (RHD), DNA-binding domain superfamily
additional property: PropertyValue
  property ID: P527
  value: ankyrin repeat-containing domain
additional property: PropertyValue
  property ID: P527
  value: Rel homology dimerisation domain
additional property: PropertyValue
  property ID: P527
  value: IPT domain
additional property: PropertyValue
  property ID: P637
  value: NP_001170840
additional property: PropertyValue
  property ID: P637
  value: NP_001170841
additional property: PropertyValue
  property ID: P637
  value: NP_062281
additional property: PropertyValue
  property ID: P638
  value: 3JV5
additional property: PropertyValue
  property ID: P638
  value: 3JV6
additional property: PropertyValue
  property ID: P680
  value: DNA binding
additional property: PropertyValue
  property ID: P680
  value: RNA polymerase II transcription regulatory region sequence-specific DNA binding
additional property: PropertyValue
  property ID: P680
  value: DNA-binding transcription factor activity
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: I-kappaB/NF-kappaB complex
additional property: PropertyValue
  property ID: P681
  value: Bcl3/NF-kappaB2 complex
additional property: PropertyValue
  property ID: P682
  value: response to cytokine
additional property: PropertyValue
  property ID: P682
  value: regulation of transcription, DNA-templated
additional property: PropertyValue
  property ID: P682
  value: rhythmic process
additional property: PropertyValue
  property ID: P702
  value: Nfkb2
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000072859
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000107512
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 11
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 11
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9WTK5
    source count: 1
    confidence: 0.2
  P361:
    value: Q24769358
    source count: 1
    confidence: 0.2
    value label: p53-like transcription factor, DNA-binding
  P361:
    value: Q24787648
    source count: 1
    confidence: 0.2
    value label: Immunoglobulin-like fold
  P361:
    value: Q41798150
    source count: 1
    confidence: 0.2
    value label: Rel homology domain (RHD), DNA-binding domain superfamily
  P361:
    value: Q24768078
    source count: 1
    confidence: 0.2
    value label: NF-kappa-B/Dorsal
  P361:
    value: Q24776395
    source count: 1
    confidence: 0.2
    value label: Death-like domain superfamily
  P527:
    value: Q24778891
    source count: 1
    confidence: 0.2
    value label: ankyrin repeat-containing domain
  P527:
    value: Q24771472
    source count: 1
    confidence: 0.2
    value label: Rel homology dimerisation domain
  P527:
    value: Q24770513
    source count: 1
    confidence: 0.2
    value label: IPT domain
  P527:
    value: Q24722412
    source count: 1
    confidence: 0.2
    value label: Rel homology domain (RHD), DNA-binding domain
  P527:
    value: Q5247322
    source count: 1
    confidence: 0.2
    value label: death domain
  P637:
    value: NP_001170840
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001170841
    source count: 1
    confidence: 0.2
  P637:
    value: NP_062281
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006526806
    source count: 1
    confidence: 0.2
  P638:
    value: 3JV5
    source count: 1
    confidence: 0.2
  P638:
    value: 3JV6
    source count: 1
    confidence: 0.2
  P680:
    value: Q14633858
    source count: 2
    confidence: 0.4
    value label: DNA binding
  P680:
    value: Q14864823
    source count: 1
    confidence: 0.2
    value label: RNA polymerase II transcription regulatory region sequence-specific DNA binding
  P680:
    value: Q14817979
    source count: 1
    confidence: 0.2
    value label: DNA-binding transcription factor activity

value: Q14817973
source count: 4
confidence: 0.8
value label: DNA-binding transcription activator activity, RNA polymerase II-specific

value: Q14817976
source count: 1
confidence: 0.2
value label: chromatin binding

value: Q79899
source count: 4
confidence: 0.8
value label: cytoplasm

value: Q15317404
source count: 1
confidence: 0.2
value label: I-kappaB/NF-kappaB complex

value: Q21113881
source count: 2
confidence: 0.4
value label: Bcl3/NF-kappaB2 complex

value: Q40260
source count: 5
confidence: 1.0
value label: nucleus

value: Q220599
source count: 3
confidence: 0.6
value label: cytosol

value: Q14860535
source count: 2
confidence: 0.4
value label: response to cytokine

value: Q14633883
source count: 3
confidence: 0.6
value label: regulation of transcription, DNA-templated

value: Q14864472
source count: 1
confidence: 0.2
value label: rhythmic process

value: Q14907863
source count: 1
confidence: 0.2
value label: germinal center formation

value: Q332154
source count: 1
confidence: 0.2
value label: ageing

value: Q18252629
source count: 1
confidence: 0.2
value label: Nfkb2

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000072859
source count: 1
confidence: 0.2

value: ENSMUSP00000107512
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-03-27

source: Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways
stated in qid: Q28585900
retrieved: 2019-02-14

source: Trophoblast giant cells express NF-kappa B2 during early mouse development
stated in qid: Q28505653
retrieved: 2019-02-14

source: Distinct activities of p52/NF-kappa B required for proper secondary lymphoid organ microarchitecture: functions enhanced by Bcl-3
stated in qid: Q28585330
retrieved: 2019-02-14

source: Role of TNF ligand and receptor family in the lymphoid organogenesis defined by gene targeting
stated in qid: Q28510883
retrieved: 2019-02-14

source: Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation
stated in qid: Q28504952
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2018-09-12

source: Q20641742
stated in qid: Q20641742
retrieved: 2019-03-18

source: ensembl Release 95
stated in qid: Q60629863

wikidata id: Q21987278
domain: protein
level: standard
html url: https://4ort.xyz/entity/nuclear-factor-of-kappa-light-polypeptide-gene-enhancer-in-b-cells-2-p49-p100
markdown url: https://4ort.xyz/entity/nuclear-factor-of-kappa-light-polypeptide-gene-enhancer-in-b-cells-2-p49-p100.md
facts url summary: https://4ort.xyz/entity/nuclear-factor-of-kappa-light-polypeptide-gene-enhancer-in-b-cells-2-p49-p100/facts.json
facts url standard: https://4ort.xyz/entity/nuclear-factor-of-kappa-light-polypeptide-gene-enhancer-in-b-cells-2-p49-p100/facts.json
facts url full: https://4ort.xyz/entity/nuclear-factor-of-kappa-light-polypeptide-gene-enhancer-in-b-cells-2-p49-p100/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-02T22:01:55.340353Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:40:56.656023+00:00Z