# Nuclear factor of activated T cells 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21121619](https://www.wikidata.org/wiki/Q21121619)  
**Source**: https://4ort.xyz/entity/nuclear-factor-of-activated-t-cells-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13469)
3. Q20641742
4. [Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
6. [Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13469&geneProductId=UniProtKB:Q13469)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13469&geneProductId=UniProtKB:Q13469)
8. [Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
9. [FOXP3 controls regulatory T cell function through cooperation with NFAT](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
10. [Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
11. [NFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
12. [Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
13. [Human VRK2 (Vaccinia-related Kinase 2) Modulates Tumor Cell Invasion by Hyperactivation of NFAT1 and Expression of Cyclooxygenase-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
14. [The LxVP and PxIxIT NFAT motifs bind jointly to overlapping epitopes on calcineurin's catalytic domain distant to the regulatory domain.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
15. [USP22 is a positive regulator of NFATc2 on promoting IL2 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
16. [The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
17. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
18. [Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
19. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
21. [Antisense-mediated loss of calcium homoeostasis endoplasmic reticulum protein (CHERP; ERPROT213-21) impairs Ca2+ mobilization, nuclear factor of activated T-cells (NFAT) activation and cell proliferation in Jurkat T-lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
22. [Antisense-mediated loss of calcium homoeostasis endoplasmic reticulum protein (CHERP; ERPROT213-21) impairs Ca2+ mobilization, nuclear factor of activated T-cells (NFAT) activation and cell proliferation in Jurkat T-lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13469&geneProductId=UniProtKB:Q13469)
23. [Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13469&geneProductId=UniProtKB:Q13469)
24. [Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
25. [ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B-cell chronic lymphocytic leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
26. [Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
27. [NFAT promotes carcinoma invasive migration through glypican-6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
28. [MicroRNA-124 Suppresses the Transactivation of Nuclear Factor of Activated T Cells by Targeting Multiple Genes and Inhibits the Proliferation of Pulmonary Artery Smooth Muscle Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13469)
29. Ensembl Release 99